Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | METAP2 | P50579 | 2/20 | 0.37 |
| ▸ | METAP1 | P53582 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.34 |
| ▸ | CASP6 | P55212 | 1/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5173798 | 0.79 | ALDH1A1 (0.54) | CYP2D6MAPTALDH1A1HPGDKDM4E | |
| SCHEMBL5699450 | 0.76 | IDO1 (0.46) | CYP2D6ALDH1A1METAP2METAP1KMT2A | |
| SCHEMBL6335916 | 0.75 | CYP2D6 (0.44) | CYP2D6ALDH1A1KDM4EMETAP2METAP1 | |
| SCHEMBL7530249 | 0.74 | ALDH1A1 (0.48) | CYP2D6MAPTALDH1A1HPGDKDM4E | |
| SCHEMBL9338070 | 0.74 | CYP2D6 (0.48) | CYP2D6MAPTALDH1A1HPGDKDM4E | |
| SCHEMBL5415754 | 0.73 | METAP2 (0.44) | CYP2D6ALDH1A1HPGDKDM4EMETAP2 | |
| SCHEMBL9617869 | 0.73 | CYP2D6 (0.43) | CYP2D6ALDH1A1KDM4EMETAP2METAP1 | |
| SCHEMBL18268231 | 0.73 | IDO1 (0.46) | CYP2D6MAPTKDM4EMETAP2METAP1 | |
| SCHEMBL8899666 | 0.72 | NCEH1 (0.36) | CYP2D6MAPTALDH1A1HPGDKDM4E | |
| SCHEMBL30674368 | 0.71 | ALDH1A1 (0.43) | CYP2D6MAPTALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7754411-B2 | Slip sheet for a planographic printing plate, production process thereof and a protected planographic printing plate and laminate thereof | TOKUSHU PAPER MFG. CO., LTD. (JP) | 2010-07-13 | — | — | US | disclosed |
| US-20060014102-A1 | Lining board for lithographic plate and its manufacturing method. and protected lithographic plate and its stack | TOKUSHU PAPER MFG. CO., LTD. (JP) | 2006-01-19 | — | — | US | disclosed |
| EP-1479824-A1 | LINING BOARD FOR LITHOGRAPHIC PLATE AND ITS MANUFACTURING METHOD, AND PROTECTED LITHOGRAPHIC PLATE AND ITS STACK | TOKUSHU PAPER MFG. CO., LTD. (JP) | 2004-11-24 | — | — | EP | disclosed |