SCHEMBL29519785

SCHEMBL29519785

O=C(O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H]1CCCN1

nearest known ligand 0.49

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
DPP7 Q9UHL4 1/20 0.44
CTSC P53634 4/20 0.43
CYP3A4 P08684 2/20 0.40
CYP2D6 P10635 2/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2C19 P33261 1/20 0.40
PRCP P42785 1/20 0.40
KLK7 P49862 3/20 0.38
CYP2C9 P11712 1/20 0.37
TSHR P16473 1/20 0.37
TERT O14746 1/20 0.37
MME P08473 1/20 0.36
TGFBR1 P36897 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25365110 0.94 MEN1 (0.48) MEN1KMT2ADPP7CTSCCYP3A4
SCHEMBL25365122 0.94 MEN1 (0.48) MEN1KMT2ADPP7CTSCCYP3A4
SCHEMBL30456801 0.94 MEN1 (0.48) MEN1KMT2ADPP7CTSCCYP3A4
SCHEMBL25365117 0.94 MEN1 (0.48) MEN1KMT2ADPP7CTSCCYP3A4
SCHEMBL29679729 0.94 MEN1 (0.41) MEN1KMT2ADPP7CTSCCYP3A4
SCHEMBL30818043 0.92 MEN1 (0.43) MEN1KMT2ADPP7CTSCCYP3A4
SCHEMBL29876570 0.92 MEN1 (0.43) MEN1KMT2ADPP7CTSCCYP3A4
SCHEMBL30193956 0.92 MEN1 (0.42) MEN1KMT2ADPP7CTSCCYP3A4
SCHEMBL30193332 0.92 MEN1 (0.42) MEN1KMT2ADPP7CTSCCYP3A4
SCHEMBL30287605 0.92 MEN1 (0.42) MEN1KMT2ADPP7CTSCCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115181173-A Preparation method of Tirzepatide 深圳市健元医药科技有限公司 2022-10-14 CN claimed
US-20240366779-A1 SELECTIVE DRUG RELEASE FROM INTERNALIZED CONJUGATES OF BIOLOGICALLY ACTIVE COMPOUNDS SEAGEN INC (US) 2024-11-07 US disclosed
EP-3990064-B1 INJECTION DEVICE SANOFI SA (FR) 2024-10-09 EP disclosed
US-12036286-B2 Selective drug release from internalized conjugates of biologically active compounds SEAGEN INC. (US) 2024-07-16 US disclosed
US-20240207427-A1 SELECTIVE DRUG RELEASE FROM INTERNALIZED CONJUGATES OF BIOLOGICALLY ACTIVE COMPOUNDS SEAGEN INC (US) 2024-06-27 US disclosed
EP-3442624-B1 NEEDLE ASSEMBLY AND DRUG DELIVERY DEVICE HAVING SUCH NEEDLE ASSEMBLY SANOFI AVENTIS DEUTSCHLAND (DE) 2023-11-22 EP disclosed
US-20230091653-A1 SELECTIVE DRUG RELEASE FROM INTERNALIZED CONJUGATES OF BIOLOGICALLY ACTIVE COMPOUNDS SEAGEN INC. 2023-03-23 US disclosed
EP-4144362-A1 COMPOSITIONS COMPRISING SHORT-ACTING HORMONES FOR TREATING OR PREVENTING OBESITY AND PUMPS COMPRISING SAID COMPOSITION Adocia (FR) 2023-03-08 EP disclosed
CN-115181173-A Preparation method of Tirzepatide 深圳市健元医药科技有限公司 2022-10-14 CN disclosed
CN-114249808-A Synthesis method of Cagrilintide 杭州诺泰澳赛诺医药技术开发有限公司 2022-03-29 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240207427-A1 SELECTIVE DRUG RELEASE FROM INTERNALIZED CONJUGATES OF BIOLOGICALLY ACTIVE COMPOUNDS CTSB, CTSE, CTSZ MEN1 1450/4885KMT2A 3707/4885DPP7 70/4885
US-20240366779-A1 SELECTIVE DRUG RELEASE FROM INTERNALIZED CONJUGATES OF BIOLOGICALLY ACTIVE COMPOUNDS CTSB, CTSE, CTSZ MEN1 1450/4885KMT2A 3707/4885DPP7 70/4885
US-12036286-B2 Selective drug release from internalized conjugates of biologically active compounds CTSB, CTSE, CTSZ MEN1 1450/4885KMT2A 3707/4885DPP7 70/4885
US-20230091653-A1 SELECTIVE DRUG RELEASE FROM INTERNALIZED CONJUGATES OF BIOLOGICALLY ACTIVE COMPOUNDS CTSB, CTSE, CTSZ MEN1 1450/4885KMT2A 3707/4885DPP7 70/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.