SCHEMBL29519824

SCHEMBL29519824

O=C(N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.59

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MDM4 O15151 3/20 0.57
TP53 P04637 3/20 0.57
CASP3 P42574 4/20 0.54
MDM2 Q00987 4/20 0.52
KMT2A Q03164 2/20 0.51
SLC17A5 Q9NRA2 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29613402 0.95 MDM4 (0.61) MDM4TP53CASP3MDM2KMT2A
SCHEMBL29366757 0.95 MDM4 (0.61) MDM4TP53CASP3MDM2KMT2A
SCHEMBL29352409 0.95 MDM4 (0.61) MDM4TP53CASP3MDM2KMT2A
SCHEMBL1486216 0.95 MDM4 (0.61) MDM4TP53CASP3MDM2KMT2A
SCHEMBL29907974 0.95 MDM4 (0.61) MDM4TP53CASP3MDM2KMT2A
SCHEMBL118370 0.95 MDM4 (0.61) MDM4TP53CASP3MDM2KMT2A
SCHEMBL30977677 0.95 MDM4 (0.61) MDM4TP53CASP3MDM2KMT2A
SCHEMBL12537019 0.95 MDM4 (0.61) MDM4TP53CASP3MDM2KMT2A
SCHEMBL30080650 0.93 MDM4 (0.53) MDM4TP53CASP3MDM2KMT2A
SCHEMBL29451083 0.93 CASP3 (0.59) MDM4TP53CASP3MDM2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114249808-B CAGRILINTIDE synthesis method 江苏诺泰澳赛诺生物制药股份有限公司 2024-11-12 CN claimed
CN-114249808-A Synthesis method of Cagrilintide 杭州诺泰澳赛诺医药技术开发有限公司 2022-03-29 CN claimed
EP-4736946-A2 AMYLIN ANALOGUES Zealand Pharma A/S (DK) 2026-05-06 EP disclosed
EP-4736945-A2 AMYLIN ANALOGUES Zealand Pharma A/S (DK) 2026-05-06 EP disclosed
EP-4074729-B1 AMYLIN ANALOGUES ZEALAND PHARMA AS (DK) 2026-04-15 EP disclosed
CN-119350469-B Method for synthesizing CAGRILINTIDE by large fragment SPPS-LPPS mixing method 杭州诺澳生物医药科技有限公司 2025-05-23 CN disclosed
CN-119661685-A Canagliflozin peptide synthesis method 杭州思诺达医药科技有限责任公司 2025-03-21 CN disclosed
US-20250064895-A1 AMYLIN ANALOGUES ZEALAND PHARMA A/S (DK) 2025-02-27 US disclosed
CN-119350469-A Method for synthesizing CAGRILINTIDE by large fragment SPPS-LPPS mixing method 杭州诺澳生物医药科技有限公司 2025-01-24 CN disclosed
CN-114249808-B CAGRILINTIDE synthesis method 江苏诺泰澳赛诺生物制药股份有限公司 2024-11-12 CN disclosed
CN-114249808-B CAGRILINTIDE synthesis method 江苏诺泰澳赛诺生物制药股份有限公司 2024-11-12 CN disclosed
US-12083164-B2 Amylin analogues ZEALAND PHARMA A/S (DK) 2024-09-10 US disclosed
CN-117986347-A Synthesis method of canagliptin 杭州思诺达医药科技有限责任公司 2024-05-07 CN disclosed
CN-117586336-A Synthesis method and application of difficult polypeptide 山东大学 2024-02-23 CN disclosed
EP-4074729-A1 AMYLIN ANALOGUES Zealand Pharma A/S (DK) 2022-10-19 EP disclosed
US-11382956-B2 Amylin analogues ZEALAND PHARMA A/S (DK) 2022-07-12 US disclosed
CN-114249808-A Synthesis method of Cagrilintide 杭州诺泰澳赛诺医药技术开发有限公司 2022-03-29 CN disclosed
CN-114249808-A Synthesis method of Cagrilintide 杭州诺泰澳赛诺医药技术开发有限公司 2022-03-29 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12083164-B2 Amylin analogues IAPP, GLP1R, AMY2A MDM4 3235/4885TP53 3331/4885CASP3 2209/4885
US-20250064895-A1 AMYLIN ANALOGUES IAPP, GLP1R, AMY2A MDM4 3235/4885TP53 3331/4885CASP3 2209/4885
US-11382956-B2 Amylin analogues IAPP, GLP1R, AMY2A MDM4 3235/4885TP53 3331/4885CASP3 2209/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.