SCHEMBL29366757

SCHEMBL29366757

O=C(N[C@H](CO)C(=O)O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.64

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MDM4 O15151 3/20 0.61
TP53 P04637 3/20 0.61
CASP3 P42574 3/20 0.58
KMT2A Q03164 2/20 0.53
MDM2 Q00987 5/20 0.52
SLC17A5 Q9NRA2 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL118370 1.00 MDM4 (0.61) MDM4TP53CASP3KMT2AMDM2
SCHEMBL30977677 1.00 MDM4 (0.61) MDM4TP53CASP3KMT2AMDM2
SCHEMBL29613402 1.00 MDM4 (0.61) MDM4TP53CASP3KMT2AMDM2
SCHEMBL12537019 1.00 MDM4 (0.61) MDM4TP53CASP3KMT2AMDM2
SCHEMBL1486216 1.00 MDM4 (0.61) MDM4TP53CASP3KMT2AMDM2
SCHEMBL29907974 1.00 MDM4 (0.61) MDM4TP53CASP3KMT2AMDM2
SCHEMBL29352409 1.00 MDM4 (0.61) MDM4TP53CASP3KMT2AMDM2
SCHEMBL29519824 0.95 MDM4 (0.57) MDM4TP53CASP3KMT2AMDM2
SCHEMBL6742006 0.92 MDM4 (0.55) MDM4TP53CASP3KMT2AMDM2
SCHEMBL29451083 0.91 CASP3 (0.59) MDM4TP53CASP3KMT2AMDM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12583889-B2 Cell penetrating peptides OXFORD UNIVERSITY INNOVATION LIMITED (GB) 2026-03-24 US disclosed
US-12371454-B2 Cyclic peptide compound having Kras inhibitory action CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-07-29 US disclosed
CN-119954892-A Whole-process targeting polypeptide, drug complex, drug delivery system and application thereof 复旦大学 2025-05-09 CN disclosed
EP-3647319-B1 PEPTIDE COMPOUND, APPLICATION THEREOF AND COMPOSITION CONTAINING SAME XDCEXPLORER SHANGHAI CO LTD (CN) 2025-04-09 EP disclosed
CN-119638792-A Polypeptide PT-09014 and application thereof in antitumor drugs 科通诺贝生物医药科技(北京)有限公司 2025-03-18 CN disclosed
CN-119504947-A Polypeptide PT-1323 and application thereof in antitumor drugs 科通诺贝生物医药科技(北京)有限公司 2025-02-25 CN disclosed
CN-119320430-A Polypeptide PT-1509 and application thereof in antitumor drugs 科通诺贝生物医药科技(北京)有限公司 2025-01-17 CN disclosed
WO-2024250929-A1 GROUP OF CYCLIC ALKALINE LIPOPEPTIDE COMPOUNDS, AND PREPARATION METHOD THEREFOR AND USE THEREOF 中国医学科学院医药生物技术研究所 2024-12-12 WO disclosed
US-20240400617-A1 CYCLIC PEPTIDE COMPOUND HAVING KRAS INHIBITORY ACTION CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2024-12-05 US disclosed
CN-119019491-A General serine short peptide synthesis method 华东理工大学 2024-11-26 CN disclosed
WO-2022162332-A1 ANTIBIOTIC NATURAL PRODUCT ANALOGUES THE QUEEN'S UNIVERSITY OF BELFAST (GB) 2022-08-04 WO disclosed
US-20220226479-A1 CELL LAYER PERMEATION PROMOTER. COMPOSITION FOR FACILITATING DRUG ABSORPTION. AND PHARMACEUTICAL COMPOSITION UNIVERSITY OF TSUKUBA (JP) 2022-07-21 US disclosed
CN-109134610-B Peptide compound, application thereof and composition containing peptide compound 尚华医药科技(江西)有限公司 2022-07-08 CN disclosed
US-20220162262-A1 NOVEL COMPOUNDS AND THERAPEUTIC USES THEREOF Centauri Therapeutics Limited (GB/GB) (GB) 2022-05-26 US disclosed
CN-111978371-B Polypeptide derivative and application thereof in field of medicine 成都诺和晟泰生物科技有限公司 2022-05-13 CN disclosed
WO-2022082006-A1 BINDING ASSAYS INVOLVING A PLURALITY OF SYNTHETIC COMPOUNDS, TARGETS, AND COUNTER TARGETS SRI INTERNATIONAL (US) 2022-04-21 WO disclosed
EP-3973990-A1 PROMOTOR FOR PERMEATION INTO CELL LAYER, COMPOSITION FOR FACILITATING DRUG AGENT ABSORPTION, AND PHARMACEUTICAL COMPOSITION University of Tsukuba (JP) 2022-03-30 EP disclosed
WO-2022054062-A1 SYNTHETIC CYCLIC PEPTIDE MIMETICS BAR ILAN UNIVERSITY (IL) 2022-03-17 WO disclosed
WO-2022050529-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE ㈜베르티스 2022-03-10 WO disclosed
CN-109311910-B Tacrolimus conjugates, compositions thereof, and uses thereof 杜兰教育基金委员会 2022-02-01 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240400617-A1 CYCLIC PEPTIDE COMPOUND HAVING KRAS INHIBITORY ACTION KRAS, NRAS, HRAS MDM4 441/4885TP53 34/4885CASP3 3906/4885
US-12583889-B2 Cell penetrating peptides SLC2A3, SLC1A5, SLC2A1 MDM4 4625/4885TP53 1977/4885CASP3 854/4885
US-20220226479-A1 CELL LAYER PERMEATION PROMOTER. COMPOSITION FOR FACILITATING DRUG ABSORPTION. AND PHARMACEUTICAL COMPOSITION ABCB11, ABCB1, SLC10A1 MDM4 4535/4885TP53 4108/4885CASP3 2986/4885
US-12371454-B2 Cyclic peptide compound having Kras inhibitory action KRAS, NRAS, HRAS MDM4 441/4885TP53 34/4885CASP3 3906/4885
US-20220162262-A1 NOVEL COMPOUNDS AND THERAPEUTIC USES THEREOF MAVS, MYD88, CD47 MDM4 3186/4885TP53 788/4885CASP3 1077/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.