SCHEMBL29519945

CC(C)C[C@H](NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CS)C(=O)N[C@@H](CS)C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 4)

	gene	UniProt	supporting neighbours	confidence
▸	MME	P08473	3/20	0.49

▸	BACE1	P56817	2/20	0.46

▸	OPRM1	P35372	1/20	0.44

▸	OPRD1	P41143	1/20	0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL31050430	0.90	MME (0.51)	MME
SCHEMBL30788364	0.90	MME (0.51)	MME
SCHEMBL29388221	0.88	ECE1 (0.57)	—
SCHEMBL31721024	0.88	MME (0.49)	MME
SCHEMBL29519856	0.87	BACE1 (0.39)	BACE1
SCHEMBL29519342	0.87	APLNR (0.40)	MMEBACE1
SCHEMBL30066857	0.87	MME (0.47)	MME
SCHEMBL29511067	0.87	MME (0.45)	MME
SCHEMBL29511244	0.86	FNTA (0.47)	MME
SCHEMBL9617697	0.86	LTA4H (0.55)	MMEOPRM1OPRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20240124612-A1	MOLECULES WITH ALTERED NEONATE FC RECEPTOR BINDING HAVING ENHANCED THERAPEUTIC AND DIAGNOSTIC PROPERTIES	MEDIMMUNE LLC	2024-04-18	—	—	US	disclosed
US-11767369-B2	Molecules with altered neonate Fc receptor binding having enhanced therapeutic and diagnostic properties	MEDIMMUNE, LLC (US)	2023-09-26	—	—	US	disclosed
CN-106413750-B	Molecules with altered neonatal Fc receptor binding with enhanced therapeutic and diagnostic properties	免疫医疗有限责任公司	2022-04-29	—	—	CN	disclosed