Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 3/20 | 0.39 |
| ▸ | CTSD | P07339 | 4/20 | 0.39 |
| ▸ | CALCR | P30988 | 4/20 | 0.38 |
| ▸ | REN | P00797 | 1/20 | 0.38 |
| ▸ | EDNRA | P25101 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | KISS1R | Q969F8 | 2/20 | 0.38 |
| ▸ | NTSR2 | O95665 | 1/20 | 0.38 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.38 |
| ▸ | APLNR | P35414 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31548689 | 0.88 | MAGI3 (0.46) | BACE1CALCRF2 | |
| SCHEMBL29615161 | 0.88 | ENPEP (0.41) | — | |
| SCHEMBL29519945 | 0.87 | MME (0.49) | BACE1 | |
| SCHEMBL30262132 | 0.86 | KISS1R (0.40) | BACE1CALCRRENEDNRAF2 | |
| SCHEMBL29519342 | 0.85 | APLNR (0.40) | BACE1CTSDF2APLNR | |
| SCHEMBL29511067 | 0.85 | MME (0.45) | — | |
| SCHEMBL30066857 | 0.85 | MME (0.47) | — | |
| SCHEMBL29641501 | 0.84 | CTSD (0.44) | BACE1CTSDRENEDNRANTSR2 | |
| SCHEMBL30006221 | 0.84 | MAGI3 (0.40) | BACE1CTSDKISS1R | |
| SCHEMBL2195704 | 0.84 | CTSD (0.37) | BACE1CTSDRENEDNRAF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240124612-A1 | MOLECULES WITH ALTERED NEONATE FC RECEPTOR BINDING HAVING ENHANCED THERAPEUTIC AND DIAGNOSTIC PROPERTIES | MEDIMMUNE LLC | 2024-04-18 | — | — | US | disclosed |
| US-11767369-B2 | Molecules with altered neonate Fc receptor binding having enhanced therapeutic and diagnostic properties | MEDIMMUNE, LLC (US) | 2023-09-26 | — | — | US | disclosed |
| CN-106413750-B | Molecules with altered neonatal Fc receptor binding with enhanced therapeutic and diagnostic properties | 免疫医疗有限责任公司 | 2022-04-29 | — | — | CN | disclosed |