Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NME2 | P22392 | 8/20 | 0.66 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 6/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 6/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 6/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 6/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 6/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 6/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29520018 | 0.88 | NME2 (0.64) | NME2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL29519693 | 0.81 | RAB9A (0.67) | NME2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL29519683 | 0.80 | MEN1 (0.60) | NME2MEN1KMT2ABLMNPC1 | |
| SCHEMBL29520052 | 0.80 | MEN1 (0.66) | NME2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL29519532 | 0.80 | RAB9A (0.68) | MEN1KMT2ANPC1RAB9A | |
| SCHEMBL29519915 | 0.73 | NME2 (0.55) | NME2MEN1KMT2ABLM | |
| SCHEMBL29519914 | 0.72 | MEN1 (0.58) | NME2MEN1KMT2ABLM | |
| SCHEMBL21993751 | 0.70 | SMARCA4 (0.60) | NME2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL29519827 | 0.70 | RAB9A (0.66) | NME2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL11084767 | 0.70 | MEN1 (0.66) | NME2MEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114249733-B | Isaindigotone derivative and application thereof in preparation of antitumor drugs | 兰州大学 | 2023-05-12 | — | — | CN | disclosed |
| CN-114249733-A | Isaindigotone derivative and application thereof in preparation of antitumor drugs | 兰州大学 | 2022-03-29 | — | — | CN | disclosed |