SCHEMBL29520199

SCHEMBL29520199

c1ccc2c(c1)[nH]c1ccc3c4ccccc4sc3c12

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TNKS O95271 2/20 0.57
TNKS2 Q9H2K2 2/20 0.57
MEN1 O00255 3/20 0.54
KMT2A Q03164 3/20 0.54
MAPT P10636 2/20 0.54
RAB9A P51151 1/20 0.54
GABRA1 P14867 2/20 0.51
GABRG2 P18507 2/20 0.51
GABRB3 P28472 2/20 0.51
GABRA5 P31644 2/20 0.51
GABRA3 P34903 2/20 0.51
GABRA2 P47869 2/20 0.51
GABRP O00591 1/20 0.51
GABRD O14764 1/20 0.51
GABRB1 P18505 1/20 0.51
GABRB2 P47870 1/20 0.51
GABRA4 P48169 1/20 0.51
GABRE P78334 1/20 0.51
GABRA6 Q16445 1/20 0.51
GABRG1 Q8N1C3 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29470199 1.00 TNKS (0.57) TNKSTNKS2MEN1KMT2AMAPT
SCHEMBL31684 1.00 TNKS (0.57) TNKSTNKS2MEN1KMT2AMAPT
SCHEMBL18926346 0.92 TNKS (0.55) TNKSTNKS2MEN1KMT2AMAPT
SCHEMBL16919355 0.91 MAPT (0.50) TNKSTNKS2MEN1KMT2AMAPT
SCHEMBL19968103 0.89 TNKS (0.50) TNKSTNKS2MEN1KMT2AMAPT
SCHEMBL11933063 0.89 GABRP (0.58) TNKSTNKS2MEN1KMT2AMAPT
SCHEMBL14653493 0.88 TNKS (0.46) TNKSTNKS2MEN1KMT2AMAPT
SCHEMBL18688070 0.87 TNKS (0.62) TNKSTNKS2MEN1KMT2AMAPT
SCHEMBL21282038 0.85 GABRP (0.49) TNKSTNKS2MEN1KMT2AMAPT
SCHEMBL14789657 0.85 CDK4 (0.43) TNKSTNKS2MEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240357926-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2024-10-24 US disclosed
EP-3898888-B1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2022-08-03 EP disclosed
US-11309497-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2022-04-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240357926-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES OR10J3, L1CAM, EPCAM TNKS 3281/4885TNKS2 3116/4885MEN1 2049/4885
US-11309497-B2 Materials for organic electroluminescent devices DDT, ESD, TST TNKS 2693/4885TNKS2 3008/4885MEN1 2814/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.