Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29520451 | 0.80 | HSD17B10 (0.40) | — | |
| SCHEMBL29520473 | 0.69 | ESR1 (0.32) | — | |
| SCHEMBL29520155 | 0.69 | MEN1 (0.38) | — | |
| SCHEMBL22188020 | 0.69 | MEN1 (0.38) | — | |
| SCHEMBL19023234 | 0.66 | — | — | |
| SCHEMBL1950399 | 0.66 | RAB9A (0.40) | NR1H2NR1H3 | |
| SCHEMBL24007234 | 0.64 | TSHR (0.36) | NR1H2 | |
| SCHEMBL31553839 | 0.62 | RAF1 (0.40) | RAF1 | |
| SCHEMBL25029042 | 0.62 | TDP2 (0.34) | — | |
| SCHEMBL29364108 | 0.62 | TDP2 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022063140-A1 | PYRIMIDINE AND PYRIDINE DERIVATIVES AS HPK1 MODULATOR AND METHODS USING SAME | SHENZHEN IONOVA LIFE SCIENCE CO., LTD. (CN) | 2022-03-31 | — | — | WO | disclosed |