Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29520263 | 0.69 | RAF1 (0.33) | — | |
| SCHEMBL29520451 | 0.69 | HSD17B10 (0.40) | HTT | |
| SCHEMBL27020187 | 0.69 | ESR1 (0.35) | ESR1ESR2 | |
| SCHEMBL3386454 | 0.67 | GRM5 (0.53) | ESR1ESR2GAARAB9A | |
| SCHEMBL3302451 | 0.66 | NAMPT (0.42) | ESR1ESR2MAPTLMNAHTT | |
| SCHEMBL30635519 | 0.66 | MAPT (0.36) | MAPT | |
| SCHEMBL29520155 | 0.66 | MEN1 (0.38) | GAAMAPTHTTRAB9A | |
| SCHEMBL22188020 | 0.66 | MEN1 (0.38) | GAAMAPTHTTRAB9A | |
| SCHEMBL31600732 | 0.65 | ADORA3 (0.35) | ESR1ESR2LMNAHTTRAB9A | |
| SCHEMBL28964104 | 0.65 | CES2 (0.42) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022063140-A1 | PYRIMIDINE AND PYRIDINE DERIVATIVES AS HPK1 MODULATOR AND METHODS USING SAME | SHENZHEN IONOVA LIFE SCIENCE CO., LTD. (CN) | 2022-03-31 | — | — | WO | disclosed |