SCHEMBL29520554

SCHEMBL29520554

CSc1ccc2c(c1)C(=C(C)C)C(c1ccccc1)=NC(C(C)(C)C)=N2

nearest known ligand 0.37

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CHRM1 P11229 1/20 0.37
DHODH Q02127 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29520545 0.84 MAPT (0.42) CHRM1
SCHEMBL29521036 0.83 CYP2C9 (0.36) CHRM1
SCHEMBL29520576 0.83 IDO1 (0.31)
SCHEMBL29520664 0.83 CHRM1 (0.39) CHRM1
SCHEMBL29520494 0.81 MAPT (0.38)
SCHEMBL28500399 0.81 MAPT (0.43) CHRM1
SCHEMBL29520828 0.81 MAPT (0.45)
SCHEMBL29520737 0.80 IDO1 (0.40)
SCHEMBL29409248 0.78 NPC1 (0.36) CHRM1
SCHEMBL29520778 0.77 CHRM1 (0.37) CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112174901-B Synthesis method and anticancer activity of 1, 3-benzodiazepine compound 河南师范大学 2022-02-08 CN disclosed