Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.37 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.37 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.37 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30461560 | 1.00 | LMNA (0.49) | LMNAALDH1A1MAPTUSP30L3MBTL1 | |
| SCHEMBL30719813 | 1.00 | LMNA (0.49) | LMNAALDH1A1MAPTUSP30L3MBTL1 | |
| SCHEMBL26424959 | 1.00 | LMNA (0.49) | LMNAALDH1A1MAPTUSP30L3MBTL1 | |
| SCHEMBL19021652 | 1.00 | LMNA (0.49) | LMNAALDH1A1MAPTUSP30L3MBTL1 | |
| SCHEMBL19021563 | 1.00 | LMNA (0.49) | LMNAALDH1A1MAPTUSP30L3MBTL1 | |
| SCHEMBL31235999 | 0.92 | LMNA (0.49) | LMNAALDH1A1MAPTUSP30L3MBTL1 | |
| SCHEMBL31235986 | 0.90 | ALDH1A1 (0.47) | LMNAALDH1A1MAPTUSP30L3MBTL1 | |
| SCHEMBL31235959 | 0.88 | LMNA (0.47) | LMNAALDH1A1MAPTUSP30L3MBTL1 | |
| SCHEMBL31543863 | 0.85 | LMNA (0.47) | LMNAALDH1A1MAPTUSP30L3MBTL1 | |
| SCHEMBL29697807 | 0.84 | L3MBTL1 (0.40) | LMNAALDH1A1MAPTL3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025067509-A1 | EGFR DEGRADANT, AND PREPARATION METHOD AND USE THEREFOR | 石药集团中奇制药技术（石家庄）有限公司 | 2025-04-03 | — | — | WO | disclosed |
| CN-116456985-A | Pyrimidine and pyridine derivatives as HPK1 modulators and methods of use thereof | 深圳市原力生命科学有限公司 | 2023-07-18 | — | — | CN | disclosed |
| WO-2022063140-A1 | PYRIMIDINE AND PYRIDINE DERIVATIVES AS HPK1 MODULATOR AND METHODS USING SAME | SHENZHEN IONOVA LIFE SCIENCE CO., LTD. (CN) | 2022-03-31 | — | — | WO | disclosed |