Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13567593 | 0.97 | ALDH1A1 (0.32) | ALDH1A1TP53CYP3A4TDP1ESR1 | |
| Hydrochloric Acid SCHEMBL11205797 | 0.89 | — | — | |
| SCHEMBL1304591 | 0.86 | — | — | |
| SCHEMBL6288069 | 0.85 | ALDH1A1 (0.50) | ALDH1A1CYP3A4TDP1MAPT | |
| Hydrochloric Acid SCHEMBL11789517 | 0.81 | ESR2 (0.50) | TP53ESR2 | |
| SCHEMBL28211634 | 0.79 | ALDH1A1 (0.43) | ALDH1A1CYP3A4TDP1MAPT | |
| SCHEMBL14600169 | 0.77 | ESR2 (0.52) | TP53TDP1ESR2 | |
| Ethyne SCHEMBL5511281 | 0.75 | ALDH1A1 (0.39) | ALDH1A1CYP3A4TDP1MAPT | |
| SCHEMBL28387184 | 0.75 | ACHE (0.37) | ALDH1A1TDP1MAPT | |
| Hydrochloric Acid SCHEMBL1578783 | 0.75 | LMNA (0.47) | ALDH1A1CYP3A4TDP1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112138537-B | Filter screen structure of photocatalytic decomposition material | 奇鼎科技股份有限公司 | 2022-04-19 | — | — | CN | disclosed |