SCHEMBL29520771

SCHEMBL29520771

COc1ccc(C(OC[C@H]2O[C@@H](n3cnc4c(=O)[nH]c(NC(C)=O)nc43)[C@H](OCOCCC#N)[C@@H]2O)(c2ccccc2)c2ccc(OC)cc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TYMP P19971 13/20 0.54
TAS1R3 Q7RTX0 2/20 0.49
TAS1R1 Q7RTX1 2/20 0.49
NT5E P21589 1/20 0.40
IMPDH2 P12268 2/20 0.38
IMPDH1 P20839 1/20 0.38
HINT1 P49773 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30859099 0.87 TYMP (0.71) TYMPTAS1R3TAS1R1IMPDH2IMPDH1
SCHEMBL19841777 0.87 TYMP (0.71) TYMPTAS1R3TAS1R1IMPDH2IMPDH1
SCHEMBL30603353 0.87 TYMP (0.52) TYMP
SCHEMBL19841776 0.86 TYMP (0.59) TYMPTAS1R3TAS1R1NT5EIMPDH2
SCHEMBL29531573 0.83 TYMP (0.57) TYMPTAS1R3TAS1R1NT5EIMPDH2
SCHEMBL22408781 0.83 TYMP (0.57) TYMPTAS1R3TAS1R1NT5EIMPDH2
SCHEMBL19362154 0.83 TYMP (0.57) TYMPTAS1R3TAS1R1NT5EIMPDH2
SCHEMBL16326506 0.83 TYMP (0.43) TYMPTAS1R3TAS1R1NT5EHINT1
SCHEMBL30540710 0.83 TYMP (0.49) TYMPTAS1R3TAS1R1NT5EIMPDH2
SCHEMBL9706215 0.83 TAS1R3 (0.60) TYMPTAS1R3TAS1R1NT5EIMPDH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12509485-B2 Method for producing nucleic acid oligomer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2025-12-30 US disclosed
US-20250145655-A1 METHOD FOR PRODUCING NUCLEIC ACID OLIGOMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2025-05-08 US disclosed
EP-4488282-A1 METHOD FOR PRODUCING NUCLEIC ACID OLIGOMER Sumitomo Chemical Company, Limited (JP) 2025-01-08 EP disclosed
WO-2022064908-A1 METHOD FOR PRODUCING NUCLEIC ACID OLIGOMER 住友化学株式会社 2022-03-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250145655-A1 METHOD FOR PRODUCING NUCLEIC ACID OLIGOMER POLRMT, RNGTT, POLM TYMP 458/4885TAS1R3 1510/4885TAS1R1 2217/4885
US-12509485-B2 Method for producing nucleic acid oligomer RNGTT, POLM, NSUN2 TYMP 365/4885TAS1R3 2210/4885TAS1R1 2455/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.