SCHEMBL29520963

SCHEMBL29520963

c1ccc(CC2CCNCC2)nc1

nearest known ligand 0.55

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GBA1 P04062 1/20 0.55
SLC6A4 P31645 7/20 0.45
ALDH1A1 P00352 1/20 0.43
ALOX15 P16050 1/20 0.43
TSHR P16473 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
KDM4E B2RXH2 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
SLC6A2 P23975 5/20 0.41
SLC6A3 Q01959 4/20 0.41
HRH4 Q9H3N8 1/20 0.41
HRH3 Q9Y5N1 1/20 0.41
HTR3A P46098 1/20 0.41
KCNH2 Q12809 1/20 0.41
CYP2D6 P10635 2/20 0.40
HRH1 P35367 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1088484 1.00 GBA1 (0.55) GBA1SLC6A4ALDH1A1ALOX15TSHR
Hydrochloric Acid SCHEMBL3300333 0.98 GBA1 (0.53) GBA1SLC6A4ALDH1A1ALOX15TSHR
Hydrochloric Acid SCHEMBL16825164 0.98 GBA1 (0.53) GBA1SLC6A4ALDH1A1ALOX15TSHR
Hydrochloric Acid SCHEMBL29463797 0.98 GBA1 (0.53) GBA1SLC6A4ALDH1A1ALOX15TSHR
SCHEMBL21078184 0.94 GBA1 (0.49) GBA1SLC6A4ALDH1A1ALOX15TSHR
Piperidine SCHEMBL5689680 0.94 GBA1 (0.49) GBA1SLC6A4ALDH1A1ALOX15TSHR
SCHEMBL18973376 0.90 SLC6A4 (0.45) GBA1SLC6A4ALDH1A1ALOX15TSHR
SCHEMBL9318723 0.90 SLC6A4 (0.45) GBA1SLC6A4ALDH1A1ALOX15TSHR
SCHEMBL1515445 0.87 SMN1; SMN2 (0.48) KDM4ESMN1; SMN2HRH3HRH1
SCHEMBL1515203 0.83 HPGD (0.49) L3MBTL1KDM4ESMN1; SMN2HRH3HRH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12344600-B2 c-Myc mRNA translation modulators and uses thereof in the treatment of cancer ANIMA BIOTECH INC. (US) 2025-07-01 US disclosed
US-20250115571-A1 OXOPIPERAZINE DERIVATIVES Inthera Bioscience AG (CH) 2025-04-10 US disclosed
US-20250109128-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2025-04-03 US disclosed
US-20240368133-A1 Compounds for the Treatment of Pain, in Particular, Neuropathic Pain, and/or Other Diseases or Disorders that are Associated with AT2R and/or AT2R Mediated Signaling CONFO THERAPEUTICS N.V. (BE) 2024-11-07 US disclosed
US-12012393-B2 Oxopiperazine derivatives Inthera Bioscience AG (CH) 2024-06-18 US disclosed
US-20220213057-A1 OXOPIPERAZINE DERIVATIVES Inthera Bioscience AG (CH) 2022-07-07 US disclosed
CN-114380825-A Substituted pyrazole fused ring derivative and preparation method and application thereof 北京志健金瑞生物医药科技有限公司 2022-04-22 CN disclosed
US-11306068-B2 Oxopiperazine derivatives Inthera Bioscience AG (CH) 2022-04-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220213057-A1 OXOPIPERAZINE DERIVATIVES CYP3A5, AQP1, AVPR2 GBA1 1097/4885SLC6A4 1254/4885ALDH1A1 411/4885
US-11306068-B2 Oxopiperazine derivatives CYP3A5, AQP1, AVPR2 GBA1 1097/4885SLC6A4 1254/4885ALDH1A1 411/4885
US-20240368133-A1 Compounds for the Treatment of Pain, in Particular, Neuropathic Pain, and/or Other Diseases or Disorders that are Associated with AT2R and/or AT2R Mediated Signaling AGTR2, AGTR1, OPRL1 GBA1 3419/4885SLC6A4 168/4885ALDH1A1 2919/4885
US-20250115571-A1 OXOPIPERAZINE DERIVATIVES CYP3A5, AQP1, AVPR2 GBA1 1097/4885SLC6A4 1254/4885ALDH1A1 411/4885
US-12344600-B2 c-Myc mRNA translation modulators and uses thereof in the treatment of cancer MYC, MYCBP, MYCBP2 GBA1 4271/4885SLC6A4 4645/4885ALDH1A1 4471/4885
US-12012393-B2 Oxopiperazine derivatives CYP3A5, AQP1, AVPR2 GBA1 1097/4885SLC6A4 1254/4885ALDH1A1 411/4885
US-20250109128-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER MYC, MYCBP, MYCBP2 GBA1 4271/4885SLC6A4 4645/4885ALDH1A1 4471/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.