Butylated Hydroxytoluene

Butylated Hydroxytoluene

SCHEMBL2952160

CCCCC(CC)(CO)CO.Cc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1.OP(O)O

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.50
SMN1; SMN2 Q16637 3/20 0.50
CA2 P00918 2/20 0.50
POLB P06746 2/20 0.50
TYR P14679 1/20 0.50
HSPA5 P11021 1/20 0.43
CYP2C9 P11712 3/20 0.42
CYP2C19 P33261 3/20 0.42
HIF1A Q16665 3/20 0.42
LMNA P02545 4/20 0.39
TSHR P16473 3/20 0.39
MAPK1 P28482 2/20 0.39
MEN1 O00255 1/20 0.39
GMNN O75496 1/20 0.39
GABBR2 O75899 1/20 0.39
TP53 P04637 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
ALOX15 P16050 1/20 0.39
NFKB1 P19838 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL727872 0.89 NR5A2 (0.44) ALDH1A1SMN1; SMN2CA2POLBTYR
Butylated Hydroxytoluene SCHEMBL2952153 0.87 CA2 (0.43) ALDH1A1SMN1; SMN2CA2POLBTYR
SCHEMBL2793568 0.84 NR5A2 (0.47) ALDH1A1SMN1; SMN2CA2POLBTYR
SCHEMBL2952154 0.83 CYP3A4 (0.34) ALDH1A1SMN1; SMN2CA2POLBTYR
SCHEMBL11262061 0.80 ALDH1A1 (0.55) ALDH1A1SMN1; SMN2CA2POLBTYR
Phosphoric Acid SCHEMBL2954109 0.78 NR5A2 (0.48) ALDH1A1SMN1; SMN2CA2POLBTYR
Butylated Hydroxytoluene SCHEMBL27452988 0.78 SMN1; SMN2 (0.75) ALDH1A1SMN1; SMN2CA2POLBTYR
Butylated Hydroxytoluene SCHEMBL28288111 0.78 CA2 (0.75) ALDH1A1SMN1; SMN2CA2POLBTYR
SCHEMBL7598159 0.77 CYP2C9 (0.40) ALDH1A1SMN1; SMN2CA2POLBTYR
SCHEMBL2951541 0.77 NR5A2 (0.42) ALDH1A1SMN1; SMN2CA2POLBTYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4251690-A1 COMPOSITIONS AND METHODS FOR PROTECTING ORGANIC POLYMERIC MATERIALS FROM THE DELETERIOUS EFFECTS EXPOSURE TO UV-C LIGHT Cytec Industries Inc. (US) 2023-10-04 EP claimed
CN-116745353-A Compositions and methods for protecting organic polymeric materials from the deleterious effects of UV-C light exposure 塞特工业公司 2023-09-12 CN claimed
WO-2023129464-A1 POLYMER COMPOSITIONS HAVING DENSIFICATION ACCELERATORS AND ROTATIONAL MOLDING PROCESSES FOR MAKING HOLLOW ARTICLES THEREFROM CYTEC INDUSTRIES INC. (US) 2023-07-06 WO claimed
EP-2864310-B1 STABILIZER COMPOSITIONS CONTAINING SUBSTITUTED CHROMAN COMPOUNDS AND METHODS OF USE CYTEC TECH CORP (US) 2022-10-26 EP claimed
US-20220212375-A1 POLYMERIC HOLLOW ARTICLES CONTAINING CHROMAN-BASED COMPOUNDS AND MADE BY ROTATIONAL MOLDING CYTEC TECHNOLOGY CORP. 2022-07-07 US claimed
US-20220169829-A1 COMPOSITIONS AND METHODS FOR PROTECTING ORGANIC POLYMERIC MATERIALS FROM THE DELETERIOUS EFFECTS OF EXPOSURE TO UV-C LIGHT CYTEC INDUSTRIES INC. (US) 2022-06-02 US claimed
WO-2022115578-A1 COMPOSITIONS AND METHODS FOR PROTECTING ORGANIC POLYMERIC MATERIALS FROM THE DELETERIOUS EFFECTS EXPOSURE TO UV-C LIGHT CYTEC INDUSTRIES INC. (US) 2022-06-02 WO claimed
US-20220153959-A1 POLYOLEFIN COMPOSITIONS CONTAINING SUBSTITUTED CHROMAN COMPOUNDS AND MOLDED ARTICLES PRODUCED THEREFROM CYTEC TECHNOLOGY CORP. 2022-05-19 US claimed
CN-110669255-B Stabilizer compositions containing substituted chroman compounds and methods of use thereof 塞特克技术公司 2021-09-14 CN claimed
US-10975278-B2 Granular stabilizer compositions for use in polymer resins and methods of making same CYTEC INDUSTRIES INC. (US) 2021-04-13 US claimed
CN-112055728-A Particulate stabilizer composition for polymer resins and process for producing the same 塞特工业公司 2020-12-08 CN claimed
EP-2652014-B1 PROCESSING ADDITIVES AND USES OF SAME IN ROTATIONAL MOLDING CYTEC TECH CORP (US) 2020-07-01 EP claimed
CN-110669255-A Stabilizer compositions containing substituted chroman compounds and methods of use thereof 塞特克技术公司 2020-01-10 CN claimed
US-20190264084-A1 GRANULAR STABILIZER COMPOSITIONS FOR USE IN POLYMER RESINS AND METHODS OF MAKING SAME CYTEC INDUSTRIES INC. (US) 2019-08-29 US claimed
US-20130145962-A1 Stabilizer Compositions Containing Substituted Chroman Compounds and Methods of Use CYTEC TECHNOLOGY CORP. (US) 2013-06-13 US claimed
US-20120146257-A1 PROCESSING ADDITIVES AND USES OF SAME IN ROTATIONAL MOLDING CYTEC TECHNOLOGY CORP. (US) 2012-06-14 US claimed
US-20100256266-A1 STABILIZER COMPOSITIONS CYTEC TECHNOLOGY CORP. (US) 2010-10-07 US claimed
US-7759417-B2 Stabilizer compositions CYTEC TECHNOLOGY CORP. (US) 2010-07-20 US claimed
US-20090149581-A1 STABILIZER COMPOSITIONS CYTEC TECHNOLOGY CORP. (US) 2009-06-11 US claimed
WO-2007136565-A1 STABILIZER COMPOSITIONS CYTEC TECHNOLOGY CORP. (US) 2007-11-29 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220212375-A1 POLYMERIC HOLLOW ARTICLES CONTAINING CHROMAN-BASED COMPOUNDS AND MADE BY ROTATIONAL MOLDING RPS7, MRPS27, F7 ALDH1A1 4376/4885SMN1; SMN2 3257/4885CA2 734/4885
US-20220153959-A1 POLYOLEFIN COMPOSITIONS CONTAINING SUBSTITUTED CHROMAN COMPOUNDS AND MOLDED ARTICLES PRODUCED THEREFROM NOTUM, PMM2, WASF2 ALDH1A1 4580/4885SMN1; SMN2 1802/4885CA2 112/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.