SCHEMBL29524977

SCHEMBL29524977

O=C(OCC(Cl)(Cl)Cl)N1CCCCC1

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.41
POLB P06746 2/20 0.41
SMN1; SMN2 Q16637 4/20 0.39
HTT P42858 3/20 0.39
ATM Q13315 2/20 0.38
THRB P10828 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
HSD11B1 P28845 1/20 0.37
TSHR P16473 2/20 0.37
MAPT P10636 2/20 0.37
HPGD P15428 1/20 0.37
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
LMNA P02545 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3150494 0.81 CA2 (0.39) ALDH1A1POLBSMN1; SMN2HTTHSD11B1
SCHEMBL11643646 0.81 ALDH1A1 (0.44) ALDH1A1POLBSMN1; SMN2HTTTSHR
SCHEMBL16932983 0.80 MAPK1 (0.42) ALDH1A1POLBSMN1; SMN2HTTATM
SCHEMBL6756428 0.80 HTT (0.44) ALDH1A1POLBSMN1; SMN2HTTATM
Hydrochloric Acid SCHEMBL11645116 0.79 CA2 (0.38) ALDH1A1POLBSMN1; SMN2HTTTSHR
SCHEMBL8720475 0.79 ALDH1A1 (0.40) ALDH1A1POLBSMN1; SMN2HTTTSHR
SCHEMBL3662063 0.79 ALDH1A1 (0.36) ALDH1A1POLBSMN1; SMN2HTTTSHR
SCHEMBL8720476 0.78 ALDH1A1 (0.39) ALDH1A1POLBSMN1; SMN2HTTTSHR
SCHEMBL15932264 0.78 ALDH1A1 (0.42) ALDH1A1POLBSMN1; SMN2HTTTSHR
SCHEMBL14243237 0.78 ALDH1A1 (0.49) ALDH1A1POLBSMN1; SMN2HTTATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114206893-A (hetero) aryl-methyl-thio-beta-D-galactopyranoside derivatives 爱杜西亚药品有限公司 2022-03-18 CN disclosed