Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | POLB | P06746 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11643646 | 0.80 | ALDH1A1 (0.44) | ALDH1A1POLBHTTSMN1; SMN2RECQL | |
| SCHEMBL6744073 | 0.79 | ALDH1A1 (0.61) | ALDH1A1POLBHTTSMN1; SMN2RECQL | |
| SCHEMBL29524977 | 0.79 | ALDH1A1 (0.41) | ALDH1A1POLBHTTSMN1; SMN2TSHR | |
| SCHEMBL15932264 | 0.77 | ALDH1A1 (0.42) | ALDH1A1POLBHTTSMN1; SMN2RECQL | |
| SCHEMBL8720476 | 0.77 | ALDH1A1 (0.39) | ALDH1A1POLBHTTSMN1; SMN2RECQL | |
| SCHEMBL3150494 | 0.76 | CA2 (0.39) | ALDH1A1POLBHTTSMN1; SMN2TSHR | |
| SCHEMBL11641933 | 0.76 | HSD11B1 (0.40) | ALDH1A1POLBHTTSMN1; SMN2TSHR | |
| SCHEMBL3662063 | 0.75 | ALDH1A1 (0.36) | ALDH1A1POLBHTTSMN1; SMN2TSHR | |
| Hydrochloric Acid SCHEMBL11645116 | 0.75 | CA2 (0.38) | ALDH1A1POLBHTTSMN1; SMN2TSHR | |
| Hydrochloric Acid SCHEMBL11641925 | 0.75 | ALDH1A1 (0.40) | ALDH1A1POLBHTTSMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776936-A | Marcfortine/paraherquamide derivatives useful as antiparasitic agents | PHARMACIA & UPJOHN COMPANY (US) | 1998-07-07 | — | — | US | claimed |
| US-5776936-A | Marcfortine/paraherquamide derivatives useful as antiparasitic agents | PHARMACIA & UPJOHN COMPANY (US) | 1998-07-07 | — | — | US | disclosed |