Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 2/20 | 0.47 |
| ▸ | KDM1A | O60341 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.45 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29525428 | 0.80 | APP (0.44) | KDM1ARAB9ACES2AKR1C3AKR1C2 | |
| SCHEMBL696251 | 0.78 | AKR1C3 (0.67) | CCR2KDM1AMEN1MAPTHTT | |
| SCHEMBL31687612 | 0.77 | CCR2 (0.46) | CCR2KDM1AMEN1MAPTHTT | |
| SCHEMBL22369879 | 0.77 | KDM1A (0.56) | CCR2KDM1AOPRL1SLC6A4 | |
| SCHEMBL23381190 | 0.76 | KMT2A (0.47) | CCR2MEN1HTTRAB9AKMT2A | |
| Hydrochloric Acid SCHEMBL20564061 | 0.76 | KDM1A (0.54) | CCR2KDM1AOPRL1SLC6A4 | |
| SCHEMBL23380255 | 0.76 | AKR1C1 (0.34) | MEN1HTTKMT2A | |
| SCHEMBL17467926 | 0.75 | AKR1C1 (0.47) | MEN1HTTKMT2AOPRM1OPRL1 | |
| SCHEMBL3116411 | 0.75 | AKR1C3 (0.60) | CCR2KDM1AAKR1C3AKR1C2OPRM1 | |
| SCHEMBL8747120 | 0.75 | AKR1C3 (0.60) | CCR2KDM1AAKR1C3AKR1C2OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111094259-B | Analgesic compounds | 里科瑞尔姆IP控股有限责任公司 | 2023-08-11 | — | — | CN | disclosed |
| US-11242327-B2 | Analgesic compounds | RECURIUM IP HOLDINGS, LLC (US) | 2022-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11242327-B2 | Analgesic compounds | INA, IK, ACHE | CCR2 894/4885KDM1A 3473/4885MEN1 4009/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.