Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH3A1 | P30838 | 7/20 | 0.50 |
| ▸ | BRD4 | O60885 | 1/20 | 0.50 |
| ▸ | NOD1 | Q9Y239 | 7/20 | 0.48 |
| ▸ | CXCL8 | P10145 | 3/20 | 0.48 |
| ▸ | NOD2 | Q9HC29 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16818904 | 1.00 | ALDH3A1 (0.50) | ALDH3A1BRD4NOD1CXCL8NOD2 | |
| SCHEMBL16818540 | 0.84 | NOD1 (0.47) | ALDH3A1BRD4NOD1CXCL8NOD2 | |
| SCHEMBL16235830 | 0.82 | PPARG (0.46) | ALDH3A1BRD4NOD1CXCL8NOD2 | |
| SCHEMBL16818821 | 0.82 | CCR2 (0.52) | ALDH3A1NOD1CXCL8NOD2LMNA | |
| SCHEMBL16818826 | 0.82 | NOD1 (0.45) | ALDH3A1BRD4NOD1CXCL8NOD2 | |
| SCHEMBL16818505 | 0.81 | NOD1 (0.44) | ALDH3A1BRD4NOD1CXCL8NOD2 | |
| SCHEMBL7214465 | 0.81 | PPARG (0.46) | ALDH3A1NOD1CXCL8NOD2LMNA | |
| SCHEMBL7213488 | 0.81 | PPARG (0.48) | ALDH3A1NOD1CXCL8NOD2LMNA | |
| SCHEMBL16818423 | 0.81 | NOD1 (0.44) | ALDH3A1NOD1CXCL8NOD2LMNA | |
| SCHEMBL23436433 | 0.81 | NOD1 (0.41) | ALDH3A1BRD4NOD1CXCL8NOD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3983409-A1 | PYRIDYL OR PYRIMIDYL MTOR KINASE INHIBITORS | GlaxoSmithKline Intellectual Property Development Limited (GB) | 2022-04-20 | — | — | EP | disclosed |