Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.39 |
| ▸ | LDHB | P07195 | 1/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ASPH | Q12797 | 1/20 | 0.35 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.35 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.35 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.35 |
| ▸ | HTR4 | Q13639 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22776609 | 1.00 | LDHA (0.39) | LDHALDHBSRD5A2PTGER4NPY5R | |
| SCHEMBL22791390 | 0.90 | KDM4E (0.35) | LDHALDHBSRD5A2PTGER4NPY5R | |
| SCHEMBL22776473 | 0.89 | KDM4E (0.36) | LDHALDHBPTGER4NPY5RL3MBTL1 | |
| SCHEMBL22776589 | 0.85 | PTGER4 (0.41) | LDHALDHBSRD5A2PTGER4NPY5R | |
| SCHEMBL22777142 | 0.84 | PTGER4 (0.53) | PTGER4 | |
| SCHEMBL22777144 | 0.84 | PTGER4 (0.53) | PTGER4 | |
| SCHEMBL29614449 | 0.84 | PTGER4 (0.53) | PTGER4 | |
| SCHEMBL22776540 | 0.83 | PTGER4 (0.42) | LDHALDHBSRD5A2PTGER4NPY5R | |
| SCHEMBL22791199 | 0.82 | HTR4 (0.44) | HTR4 | |
| SCHEMBL22776455 | 0.81 | HTR4 (0.34) | PTGER4NPY5RFTOHTR4TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3983412-A1 | PROSTAGLANDIN E2 RECEPTOR 4 ANTAGONISTS AND USES THEREOF | Teon Therapeutics, Inc. (US) | 2022-04-20 | — | — | EP | disclosed |
| CN-114206866-A | Prostaglandin E2Receptor 4 antagonists and uses thereof | 泰昂治疗公司 | 2022-03-18 | — | — | CN | disclosed |