SCHEMBL29528489

SCHEMBL29528489

Cc1cc(Cl)ccc1NC(=O)CC(=O)Nc1ccc(Cl)cc1C

nearest known ligand 0.68

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.68
MEN1 O00255 4/20 0.68
POLB P06746 5/20 0.62
MAPK1 P28482 1/20 0.59
NOX1 Q9Y5S8 1/20 0.59
ALDH1A1 P00352 4/20 0.57
SMN1; SMN2 Q16637 3/20 0.57
HTT P42858 1/20 0.57
GAA P10253 3/20 0.57
MAPT P10636 3/20 0.57
KDM4E B2RXH2 1/20 0.57
HPGD P15428 1/20 0.57
TSHR P16473 1/20 0.57
TDP1 Q9NUW8 1/20 0.57
NPC1 O15118 1/20 0.56
RAB9A P51151 1/20 0.56
LMNA P02545 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8824873 0.91 KMT2A (0.61) KMT2AMEN1POLBMAPK1NOX1
SCHEMBL31570088 0.91 KMT2A (0.61) KMT2AMEN1POLBMAPK1NOX1
SCHEMBL29048142 0.90 KMT2A (0.59) KMT2AMEN1POLBMAPK1NOX1
SCHEMBL29528302 0.89 ALDH1A1 (0.73) KMT2AMEN1POLBMAPK1NOX1
SCHEMBL10603640 0.89 ALDH1A1 (0.73) KMT2AMEN1POLBMAPK1NOX1
SCHEMBL29208261 0.86 ALDH1A1 (0.62) KMT2AMEN1POLBMAPK1NOX1
SCHEMBL25360904 0.86 MEN1 (0.72) KMT2AMEN1POLBMAPK1ALDH1A1
SCHEMBL11574112 0.85 MEN1 (0.58) KMT2AMEN1POLBMAPK1NOX1
SCHEMBL6118251 0.85 MAPK1 (0.63) KMT2AMEN1POLBMAPK1NOX1
SCHEMBL10970084 0.85 KMT2A (0.54) KMT2AMEN1POLBMAPK1NOX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230339906-A1 A PROCESS FOR THE SYNTHESIS OF ANTHRANILIC ACID/AMIDE COMPOUNDS AND INTERMEDIATES THEREOF PI INDUSTRIES LTD. (IN) 2023-10-26 US disclosed
EP-4217339-A1 A PROCESS FOR THE SYNTHESIS OF ANTHRANILIC ACID/AMIDE COMPOUNDS AND INTERMEDIATES THEREOF PI Industries Ltd. (IN) 2023-08-02 EP disclosed
WO-2022064454-A1 A PROCESS FOR THE SYNTHESIS OF ANTHRANILIC ACID/AMIDE COMPOUNDS AND INTERMEDIATES THEREOF PI INDUSTRIES LTD. (IN) 2022-03-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230339906-A1 A PROCESS FOR THE SYNTHESIS OF ANTHRANILIC ACID/AMIDE COMPOUNDS AND INTERMEDIATES THEREOF ASS1, ARG1, NQO2 KMT2A 273/4885MEN1 1377/4885POLB 861/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.