Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MDM4 | O15151 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22995734 | 1.00 | TSHR (0.55) | TSHRTHRBHCAR2CYP1A2CYP2D6 | |
| SCHEMBL28237261 | 0.95 | TSHR (0.50) | TSHRTHRBHCAR2CYP1A2CYP2D6 | |
| Acrylic Acid Methyl Ester SCHEMBL28001520 | 0.94 | TSHR (0.49) | TSHRTHRBHCAR2CYP1A2CYP2D6 | |
| Methacrylic Acid SCHEMBL28196914 | 0.93 | TSHR (0.47) | TSHRTHRBHCAR2CYP1A2CYP2D6 | |
| SCHEMBL3169558 | 0.84 | THRB (0.53) | TSHRTHRBHCAR2CYP1A2CYP2D6 | |
| Acrylic Acid SCHEMBL28237259 | 0.84 | HCAR2 (0.40) | TSHRTHRBHCAR2CYP1A2CYP2D6 | |
| SCHEMBL27522725 | 0.84 | TSHR (0.51) | TSHRTHRBCYP1A2CYP2D6SMN1; SMN2 | |
| SCHEMBL5070208 | 0.84 | THRB (0.54) | TSHRTHRBHCAR2CYP2C19TRPA1 | |
| SCHEMBL17460170 | 0.83 | CYP2D6 (0.61) | TSHRTHRBHCAR2CYP1A2CYP2D6 | |
| SCHEMBL22047091 | 0.81 | THRB (0.51) | TSHRTHRBHCAR2SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112279959-A | Ophthalmic polymer material, method for the production and use thereof | 康小林 | 2021-01-29 | — | — | CN | claimed |
| US-RE38935-E1 | Intraocular lenses made from polymeric compositions and monomers useful in said compositions | ADVANCED MEDICAL OPTICS, INC. (US) | 2006-01-10 | — | — | US | claimed |
| US-6645246-B1 | Intraocular lens with surrounded lens zone | ADVANCED MEDICAL OPTICS, INC. | 2003-11-11 | — | — | US | claimed |
| US-6245106-B1 | DEFORMABLE INTRAOCULAR LENSES HAVING REDUCED SURFACE TACKINESS MADE FROM 2-PHENYLPROPYL ACRYLATE/METHACRYLATE BASED COMPOSITIONS, FOR INSERTION INTO A MAMMALIAN EYE FOR VISION CORRECTION | ALLERGAN SALES, INC. | 2001-06-12 | — | — | US | claimed |
| WO-2000060383-A1 | INTRAOCULAR LENSES MADE FROM POLYMERIC COMPOSITIONS AND MONOMERS USEFUL IN SAID COMPOSITIONS | ALLERGAN SALES, INC. (US) | 2000-10-12 | — | — | WO | claimed |
| US-12611296-B2 | Intraocular lens materials and components | ALCON INC. (CH) | 2026-04-28 | — | — | US | disclosed |
| EP-4267708-B1 | THERMALLY RESPONSIVE BRUSH POLYMERS HAVING A COPOLYMER BACKBONE AND COPOLYMER ARMS | INFINEUM INT LTD (GB) | 2025-07-02 | — | — | EP | disclosed |
| US-12281203-B2 | Thermally responsive brush polymers having a copolymer backbone and copolymer arms | INFINEUM INTERNATIONAL LIMITED (GB) | 2025-04-22 | — | — | US | disclosed |
| US-20240350256-A1 | INTRAOCULAR LENS MATERIALS AND COMPONENTS | ALCON INC. (CH) | 2024-10-24 | — | — | US | disclosed |
| US-20240309155-A1 | Thermally Responsive Brush Polymers Having a Copolymer Backbone and Copolymer Arms | INFINEUM INTERNATIONAL LIMITED (GB) | 2024-09-19 | — | — | US | disclosed |
| US-12059342-B2 | Intraocular lens materials and components | ALCON INC. (CH) | 2024-08-13 | — | — | US | disclosed |
| CN-114075122-B | Hydrophilic azo compound and application thereof | 康小林 | 2024-01-02 | — | — | CN | disclosed |
| US-5147867-A | Bactericides, (carba)penicillins | MERCK & CO., INC. (US) | 1992-09-15 | — | — | US | disclosed |
| US-5145990-A | Dehydropeptidase, carbapenicillin potentiation | MERCK & CO., INC. (US) | 1992-09-08 | — | — | US | disclosed |
| US-4962097-A | IN COMBINATION WITH A CARBAPENEM OR PENEM ANTIBIOTIC | MERCK & CO., INC. (US) | 1990-10-09 | — | — | US | disclosed |
| EP-0366469-A2 | Phosphorus containing enzyme inhibitors | MERCK & CO. INC. (US) | 1990-05-02 | — | — | EP | disclosed |
| US-4737558-A | MONOMER CONTAINING BENZENE RING AND VINYL FUNCTIONALITY; MACHINEABLE, WETTABLE | ALCON LABORATORIES, INC. (US) | 1988-04-12 | — | — | US | disclosed |
| US-4690993-A | p-(2-Hydroxy hexafluoroisopropyl) styrene [HFIS] monomer for ophthalmic applications | ALCON LABORATORIES, INC. (US) | 1987-09-01 | — | — | US | disclosed |
| US-4640941-A | CONTACT LENSES; IMPROVED OXYGEN PERMEABILITY | ALCON LABORATORIES (US) | 1987-02-03 | — | — | US | disclosed |
| US-4633003-A | CONTACT LENSES, IMPLANTS; PHENYL RING AND ACRYLIC AMIDE OR ESTER FUNCTIONALITIES | ALCON LABORATORIES, INC. (US) | 1986-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12611296-B2 | Intraocular lens materials and components | CRYAA, AQP4, CRYZ | TSHR 1038/4885THRB 1099/4885HCAR2 1670/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.