Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | GRM4 | Q14833 | 5/20 | 0.38 |
| ▸ | HSPA9 | P38646 | 1/20 | 0.37 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | GCK | P35557 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28883221 | 0.80 | ALDH1A1 (0.42) | TNKSALDH1A1MGLLGRM4HSPA9 | |
| SCHEMBL28883224 | 0.80 | ALDH1A1 (0.42) | TNKSALDH1A1MGLLGRM4HSPA9 | |
| SCHEMBL3620307 | 0.78 | TNKS (0.52) | TNKSALDH1A1HSPA9SMYD3CYP1A2 | |
| SCHEMBL12181482 | 0.75 | MEN1 (0.54) | TNKSALDH1A1CYP1A2SMN1; SMN2GAA | |
| SCHEMBL29529071 | 0.74 | ALDH1A1 (0.44) | TNKSALDH1A1MGLLGRM4HSPA9 | |
| SCHEMBL5738394 | 0.74 | TSHR (0.60) | TNKSALDH1A1CYP1A2SMN1; SMN2GAA | |
| SCHEMBL29528959 | 0.74 | ALDH1A1 (0.44) | TNKSALDH1A1MGLLGRM4HSPA9 | |
| SCHEMBL3874026 | 0.72 | HRH3 (0.48) | TNKSALDH1A1HSPA9 | |
| SCHEMBL29529436 | 0.71 | TNKS (0.47) | TNKSALDH1A1GRM4MEN1TSHR | |
| SCHEMBL5774113 | 0.71 | TNKS (0.45) | TNKSALDH1A1SMYD3CYP1A2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109415358-B | 6-aminopyridin-3-ylthiazoles as ROR gamma t modulators | 詹森药业有限公司 | 2022-04-05 | — | — | CN | disclosed |