Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TNKS | O95271 | 1/20 | 0.41 |
| ▸ | HSPA9 | P38646 | 1/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 7/20 | 0.37 |
| ▸ | HTR3A | P46098 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 2/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.35 |
| ▸ | RBBP9 | O75884 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28883224 | 1.00 | ALDH1A1 (0.42) | ALDH1A1TNKSHSPA9GRM4HTR3A | |
| SCHEMBL29529071 | 0.81 | ALDH1A1 (0.44) | ALDH1A1TNKSHSPA9GRM4HTR3A | |
| SCHEMBL29528802 | 0.80 | TNKS (0.42) | ALDH1A1TNKSHSPA9GRM4KMT2A | |
| SCHEMBL3620307 | 0.79 | TNKS (0.52) | ALDH1A1TNKSHSPA9KMT2AMEN1 | |
| SCHEMBL12181482 | 0.76 | MEN1 (0.54) | ALDH1A1TNKSKMT2AMEN1TSHR | |
| SCHEMBL29528959 | 0.75 | ALDH1A1 (0.44) | ALDH1A1TNKSHSPA9GRM4HTR3A | |
| SCHEMBL5738394 | 0.75 | TSHR (0.60) | ALDH1A1TNKSKMT2AMEN1TSHR | |
| SCHEMBL29529436 | 0.72 | TNKS (0.47) | ALDH1A1TNKSGRM4KMT2AMEN1 | |
| SCHEMBL5774113 | 0.72 | TNKS (0.45) | ALDH1A1TNKSKMT2AMEN1TSHR | |
| SCHEMBL28213918 | 0.72 | ALDH1A1 (0.53) | ALDH1A1HSPA9GRM4KMT2ACASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109415358-B | 6-aminopyridin-3-ylthiazoles as ROR gamma t modulators | 詹森药业有限公司 | 2022-04-05 | — | — | CN | disclosed |