SCHEMBL29529348

SCHEMBL29529348

CC(=O)c1ccsc1C1CCCC1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCC1 P33527 1/20 0.39
ABCG2 Q9UNQ0 1/20 0.39
MAPK10 P53779 2/20 0.38
HTT P42858 1/20 0.38
LMNA P02545 1/20 0.37
PTK2 Q05397 1/20 0.34
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
CRBN Q96SW2 1/20 0.34
ALDH1A1 P00352 3/20 0.33
ACMSD Q8TDX5 2/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
CAMKK1 Q8N5S9 2/20 0.33
CAMKK2 Q96RR4 2/20 0.33
TSHR P16473 2/20 0.33
GLS O94925 1/20 0.33
HSD17B10 Q99714 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14862766 0.85 MAPK10 (0.40) ABCC1ABCG2MAPK10HTTLMNA
SCHEMBL2550311 0.81 ABCC1 (0.38) ABCC1ABCG2MAPK10HTTLMNA
SCHEMBL2555585 0.77 MAPK10 (0.38) ABCC1ABCG2MAPK10HTTLMNA
SCHEMBL23413476 0.76 PTPN2 (0.46) ABCC1ABCG2MAPK10LMNAALDH1A1
SCHEMBL29529418 0.76 LMNA (0.36) MAPK10HTTLMNANPC1RAB9A
SCHEMBL20521813 0.74 MAPT (0.52) MAPK10HTTLMNAPTK2NPC1
SCHEMBL4556834 0.70 PRNP (0.45) ABCC1MAPK10HTTLMNAPTK2
SCHEMBL11147061 0.69 PTGDR2 (0.38) ABCC1ABCG2MAPK10HTT
SCHEMBL17164879 0.68 MAPT (0.44) MAPK10HTTLMNAPTK2NPC1
Hydrochloric Acid SCHEMBL31247929 0.68 PTPN2 (0.39) ABCC1ABCG2ALDH1A1CYP2D6TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114213370-B Method for synthesizing alkylated electron-rich heterocyclic aromatic hydrocarbon by photo-induced NHPI ester decarboxylation coupling 中山大学 2023-10-27 CN disclosed
CN-114213370-A Method for synthesizing alkylated electron-rich heterocyclic aromatic hydrocarbon by virtue of photoinduced decarboxylation coupling of NHPI ester 中山大学 2022-03-22 CN disclosed