Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC1 | P33527 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.33 |
| ▸ | PTPRB | P23467 | 1/20 | 0.33 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14862766 | 0.96 | MAPK10 (0.40) | ABCC1ABCG2MAPK10HTTLMNA | |
| SCHEMBL2555585 | 0.92 | MAPK10 (0.38) | ABCC1ABCG2MAPK10HTTLMNA | |
| SCHEMBL29529348 | 0.81 | ABCC1 (0.39) | ABCC1ABCG2MAPK10HTTLMNA | |
| SCHEMBL23413476 | 0.78 | PTPN2 (0.46) | ABCC1ABCG2MAPK10LMNAALDH1A1 | |
| SCHEMBL20521813 | 0.77 | MAPT (0.52) | MAPK10HTTLMNAALDH1A1MEN1 | |
| SCHEMBL2550314 | 0.71 | CYP2A6 (0.36) | LMNAMEN1KMT2ATDP1 | |
| SCHEMBL29529418 | 0.71 | LMNA (0.36) | MAPK10HTTLMNAALDH1A1MEN1 | |
| SCHEMBL17164879 | 0.70 | MAPT (0.44) | MAPK10HTTLMNAALDH1A1MEN1 | |
| SCHEMBL4206522 | 0.70 | MEN1 (0.44) | MAPK10HTTALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL31247929 | 0.70 | PTPN2 (0.39) | ABCC1ABCG2ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011123937-A1 | KINASE INHIBITORS AND METHOD OF TREATING CANCER WITH SAME | UNIVERSITY HEALTH NETWORK (CA) | 2011-10-13 | — | — | WO | disclosed |