Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.49 |
| ▸ | AOC1 | P19801 | 7/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 7/20 | 0.39 |
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25321326 | 1.00 | LOXL2 (0.49) | LOXL2AOC1AOC3SGMS2ALOX5AP | |
| SCHEMBL25319948 | 0.83 | SGMS2 (0.39) | LOXL2AOC1AOC3SGMS2MAOB | |
| SCHEMBL29530172 | 0.77 | FEN1 (0.47) | SGMS2ALOX5APFEN1 | |
| SCHEMBL25320280 | 0.77 | FEN1 (0.47) | SGMS2ALOX5APFEN1 | |
| SCHEMBL29102392 | 0.77 | SGMS2 (0.35) | AOC1AOC3SGMS2HDAC1HDAC6 | |
| SCHEMBL29102375 | 0.76 | KDM4C (0.45) | SGMS2MEN1KMT2A | |
| SCHEMBL17962510 | 0.75 | AOC3 (0.55) | LOXL2AOC1AOC3SGMS2HTR1A | |
| SCHEMBL25321760 | 0.74 | LOXL2 (0.44) | LOXL2AOC1AOC3MEN1KMT2A | |
| SCHEMBL29530331 | 0.74 | LOXL2 (0.44) | LOXL2AOC1AOC3MEN1KMT2A | |
| SCHEMBL25320177 | 0.73 | AOC3 (0.40) | LOXL2AOC1AOC3ALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4217070-A1 | PYRROLO[3,2-C]PYRIDIN-4-ONE DERIVATIVES USEFUL IN THE TREATMENT OF CANCER | Scorpion Therapeutics, Inc. (US) | 2023-08-02 | — | — | EP | disclosed |
| WO-2022066734-A1 | PYRROLO[3,2-C]PYRIDIN-4-ONE DERIVATIVES USEFUL IN THE TREATMENT OF CANCER | SCORPION THERAPEUTICS, INC. (US) | 2022-03-31 | — | — | WO | disclosed |