Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20424119 | 1.00 | CYP1A2 (0.37) | CYP1A2CYP2C9ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL28526308 | 0.95 | ALDH1A1 (0.41) | CYP1A2CYP2C9ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL30675350 | 0.95 | ALDH1A1 (0.41) | CYP1A2CYP2C9ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL28521203 | 0.95 | ALDH1A1 (0.41) | CYP1A2CYP2C9ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL22978699 | 0.93 | ALDH1A1 (0.44) | CYP1A2CYP2C9ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL4751832 | 0.91 | ALDH1A1 (0.36) | CYP1A2CYP2C9ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL2654623 | 0.84 | TSHR (0.40) | CYP1A2CYP2C9ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL17894913 | 0.81 | TSHR (0.53) | CYP1A2CYP2C9POLBSMN1; SMN2LMNA | |
| SCHEMBL4751947 | 0.81 | CA2 (0.42) | CYP1A2SMN1; SMN2HSD11B1 | |
| SCHEMBL12207096 | 0.80 | TPSAB1 (0.39) | CYP1A2CYP2C9ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4217070-A1 | PYRROLO[3,2-C]PYRIDIN-4-ONE DERIVATIVES USEFUL IN THE TREATMENT OF CANCER | Scorpion Therapeutics, Inc. (US) | 2023-08-02 | — | — | EP | disclosed |
| WO-2022066734-A1 | PYRROLO[3,2-C]PYRIDIN-4-ONE DERIVATIVES USEFUL IN THE TREATMENT OF CANCER | SCORPION THERAPEUTICS, INC. (US) | 2022-03-31 | — | — | WO | disclosed |