Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 3/20 | 1.00 |
| ▸ | CA1 | P00915 | 1/20 | 0.68 |
| ▸ | CA2 | P00918 | 1/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | GMNN | O75496 | 1/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | IDE | P14735 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10548485 | 1.00 | TRPV1 (1.00) | TRPV1CA1CA2HSD17B10MAPT | |
| SCHEMBL28942175 | 1.00 | TRPV1 (1.00) | TRPV1CA1CA2HSD17B10MAPT | |
| SCHEMBL159764 | 0.92 | TRPV1 (0.85) | TRPV1CA1CA2HSD17B10MAPT | |
| SCHEMBL155979 | 0.92 | TRPV1 (0.85) | TRPV1CA1CA2HSD17B10MAPT | |
| SCHEMBL155980 | 0.92 | TRPV1 (0.85) | TRPV1CA1CA2HSD17B10MAPT | |
| SCHEMBL30475690 | 0.88 | TRPV1 (0.78) | TRPV1CA1CA2HSD17B10MAPT | |
| SCHEMBL6161575 | 0.87 | TRPV1 (0.78) | TRPV1CA1CA2HSD17B10MAPT | |
| Hydrocaffeoylhexylamide SCHEMBL9346647 | 0.86 | TRPV1 (0.80) | TRPV1HSD17B10MAPTMEN1KMT2A | |
| SCHEMBL9345367 | 0.86 | TRPV1 (0.80) | TRPV1HSD17B10MAPTMEN1KMT2A | |
| SCHEMBL9350021 | 0.86 | TRPV1 (0.80) | TRPV1HSD17B10MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114315631-B | Capsaicin derivative, and preparation method and application thereof | 广西医科大学 | 2024-01-05 | — | — | CN | disclosed |
| CN-114315631-A | Capsaicin derivative and preparation method and application thereof | 广西医科大学 | 2022-04-12 | — | — | CN | disclosed |