SCHEMBL29530889

CC(C)C[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)O

nearest known ligand 0.62

Predicted protein targets (top 3)

	gene	UniProt	supporting neighbours	confidence
▸	KISS1R	Q969F8	18/20	0.62

▸	ERAP2	Q6P179	2/20	0.57

▸	IL1RN	P18510	1/20	0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29530905	1.00	KISS1R (0.62)	KISS1RERAP2IL1RN
SCHEMBL9222562	0.93	KISS1R (0.65)	KISS1RERAP2IL1RN
SCHEMBL9222572	0.93	KISS1R (0.65)	KISS1RERAP2IL1RN
SCHEMBL30864211	0.89	OPRM1 (0.54)	KISS1R
SCHEMBL31343242	0.87	ERAP2 (0.62)	KISS1RERAP2IL1RN
SCHEMBL29403649	0.86	NPY4R (0.55)	KISS1RERAP2IL1RN
SCHEMBL29531366	0.86	NPY4R (0.55)	KISS1RERAP2IL1RN
SCHEMBL29531210	0.86	NPY4R (0.55)	KISS1RERAP2IL1RN
SCHEMBL29496461	0.86	BACE1 (0.57)	KISS1R
SCHEMBL29530897	0.86	NPY4R (0.55)	KISS1RERAP2IL1RN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-12312390-B2	Rapid-acting insulin analogues of enhanced stability	CASE WESTERN RESERVE UNIVERSITY (US)	2025-05-27	—	—	US	disclosed
US-20220112262-A1	RAPID-ACTING INSULIN ANALOGUES OF ENHANCED STABILITY	CASE WESTERN RESERVE UNIVERSITY	2022-04-14	—	—	US	disclosed