SCHEMBL9222572

SCHEMBL9222572

CC(C)C[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)C(=O)O

nearest known ligand 0.65

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ KISS1R Q969F8 19/20 0.65
▸ IL1RN P18510 1/20 0.61
▸ ERAP2 Q6P179 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9222562 1.00 KISS1R (0.65) KISS1RIL1RNERAP2
SCHEMBL29530889 0.93 KISS1R (0.62) KISS1RIL1RNERAP2
SCHEMBL29530905 0.93 KISS1R (0.62) KISS1RIL1RNERAP2
SCHEMBL29362362 0.91 ERAP2 (0.69) KISS1RIL1RNERAP2
SCHEMBL29362220 0.90 OPRM1 (0.59) IL1RNERAP2
SCHEMBL31672259 0.88 KISS1R (0.65) KISS1R
SCHEMBL30418018 0.88 OPRM1 (0.59) KISS1RERAP2
SCHEMBL31606469 0.88 ERAP2 (0.64) KISS1RIL1RNERAP2
SCHEMBL31609332 0.88 ERAP2 (0.63) KISS1RIL1RNERAP2
SCHEMBL30123487 0.87 OPRM1 (0.59) IL1RNERAP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0198015-B2 PRODUCTION OF STREPTAVIDIN-LIKE POLYPEPTIDES BIOGEN INC (US) 1995-07-19 — — EP disclosed
US-5168049-A Hybrid DNA sequences expressing fused proteins BIOGEN, INC. (US) 1992-12-01 — — US disclosed
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