Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 8/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | NPY1R | P25929 | 1/20 | 0.43 |
| ▸ | NPY2R | P49146 | 1/20 | 0.43 |
| ▸ | NPY4R | P50391 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | MME | P08473 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | CPA1 | P15085 | 1/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30843955 | 1.00 | OPRD1 (0.46) | OPRD1OPRM1OPRK1NPY1RNPY2R | |
| SCHEMBL31199054 | 0.92 | OPRD1 (0.44) | OPRD1OPRM1OPRK1NPY1RNPY2R | |
| SCHEMBL29629478 | 0.91 | LNPEP (0.44) | OPRD1OPRM1NPY1RNPY2RNPY4R | |
| SCHEMBL30843968 | 0.90 | NPY4R (0.44) | OPRD1OPRM1NPY1RNPY2RNPY4R | |
| SCHEMBL30567410 | 0.90 | BACE1 (0.38) | OPRD1OPRM1BACE1MME | |
| SCHEMBL30254038 | 0.90 | BACE1 (0.38) | OPRD1OPRM1BACE1MME | |
| SCHEMBL30426861 | 0.90 | OPRD1 (0.56) | OPRD1OPRM1OPRK1 | |
| SCHEMBL29590286 | 0.89 | FNTA (0.43) | OPRD1OPRM1NPY1RNPY2RNPY4R | |
| SCHEMBL30629018 | 0.89 | MME (0.47) | OPRD1OPRM1NPY1RNPY2RNPY4R | |
| SCHEMBL29655487 | 0.88 | BACE1 (0.54) | OPRD1OPRM1BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230393140-A1 | BINDING ASSAYS INVOLVING A PLURALITY OF SYNTHETIC COMPOUNDS, TARGETS, AND COUNTER TARGETS | SRI INTERNATIONAL (US) | 2023-12-07 | — | — | US | disclosed |
| EP-4229211-A1 | BINDING ASSAYS INVOLVING A PLURALITY OF SYNTHETIC COMPOUNDS, TARGETS, AND COUNTER TARGETS | SRI International (US) | 2023-08-23 | — | — | EP | disclosed |
| WO-2022082006-A1 | BINDING ASSAYS INVOLVING A PLURALITY OF SYNTHETIC COMPOUNDS, TARGETS, AND COUNTER TARGETS | SRI INTERNATIONAL (US) | 2022-04-21 | — | — | WO | disclosed |