SCHEMBL29629478

SCHEMBL29629478

CC(C)[C@H](N)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](C(=O)O)C(C)C

nearest known ligand 0.44

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ LNPEP Q9UIQ6 7/20 0.44
▸ ANPEP P15144 4/20 0.44
▸ OPRD1 P41143 2/20 0.41
▸ OPRM1 P35372 1/20 0.41
▸ MME P08473 3/20 0.40
▸ ACE P12821 2/20 0.40
▸ CPA1 P15085 1/20 0.40
▸ ACE2 Q9BYF1 1/20 0.40
▸ ENPEP Q07075 2/20 0.39
▸ NPY1R P25929 1/20 0.39
▸ NPY2R P49146 1/20 0.39
▸ NPY4R P50391 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29531471 0.93 ACE (0.47) LNPEPANPEPOPRD1MMEACE
SCHEMBL30843955 0.91 OPRD1 (0.46) OPRD1OPRM1MMEACECPA1
SCHEMBL29531463 0.91 OPRD1 (0.46) OPRD1OPRM1MMEACECPA1
SCHEMBL29881377 0.91 CTSD (0.35) LNPEPANPEPMME
SCHEMBL31274737 0.91 MME (0.50) LNPEPANPEPOPRD1MMEACE
SCHEMBL30670300 0.89 LNPEP (0.54) LNPEPANPEPMMEACECPA1
SCHEMBL31049654 0.89 CTSD (0.38) LNPEPANPEPMME
SCHEMBL30843968 0.88 NPY4R (0.44) OPRD1OPRM1NPY1RNPY2RNPY4R
SCHEMBL29350566 0.87 MME (0.50) LNPEPANPEPOPRD1OPRM1MME
SCHEMBL29386631 0.87 MME (0.50) LNPEPANPEPOPRD1OPRM1MME

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3938378-B1 NOROVIRUS-LIKE PARTICLES WITH IMPROVED STABILITY ICON GENETICS GMBH (DE) 2023-08-02 — — EP claimed
US-20220152186-A1 NOROVIRUS-LIKE PARTICLES WITH IMPROVED STABILITY ICON GENETICS GMBH (DE) 2022-05-19 — — US claimed
CN-113557240-B Norovirus-like particles with improved stability 爱康遗传有限公司 2025-02-25 — — CN disclosed
EP-3938378-B1 NOROVIRUS-LIKE PARTICLES WITH IMPROVED STABILITY ICON GENETICS GMBH (DE) 2023-08-02 — — EP disclosed
US-20220152186-A1 NOROVIRUS-LIKE PARTICLES WITH IMPROVED STABILITY ICON GENETICS GMBH (DE) 2022-05-19 — — US disclosed
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