Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 3/20 | 0.54 |
| ▸ | C5AR1 | P21730 | 2/20 | 0.54 |
| ▸ | PLK1 | P53350 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 3/20 | 0.47 |
| ▸ | CTSS | P25774 | 3/20 | 0.47 |
| ▸ | CTSK | P43235 | 3/20 | 0.47 |
| ▸ | CTSH | P09668 | 1/20 | 0.47 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.47 |
| ▸ | RAMP3 | O60896 | 5/20 | 0.46 |
| ▸ | CALCR | P30988 | 5/20 | 0.46 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30398324 | 0.90 | APLNR (0.54) | APLNRC5AR1PLK1CTSLCTSS | |
| SCHEMBL29607506 | 0.88 | APLNR (0.56) | APLNRC5AR1PLK1CTSLCTSS | |
| SCHEMBL30753783 | 0.88 | CTSL (0.53) | APLNRC5AR1CTSLCTSSCTSK | |
| SCHEMBL29606819 | 0.88 | APLNR (0.57) | APLNRC5AR1PLK1CTSLCTSS | |
| SCHEMBL29607035 | 0.88 | APLNR (0.55) | APLNRC5AR1PLK1CTSLCTSS | |
| SCHEMBL29607754 | 0.87 | APLNR (0.56) | APLNRC5AR1PLK1CTSLCTSS | |
| SCHEMBL9295105 | 0.87 | C5AR1 (0.52) | APLNRC5AR1PLK1CTSLCTSS | |
| SCHEMBL30753782 | 0.86 | APLNR (0.57) | APLNRC5AR1PLK1EPHA2 | |
| SCHEMBL29608843 | 0.86 | C5AR1 (0.58) | APLNRC5AR1CXCR4 | |
| SCHEMBL29608840 | 0.86 | C5AR1 (0.58) | APLNRC5AR1CXCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230393140-A1 | BINDING ASSAYS INVOLVING A PLURALITY OF SYNTHETIC COMPOUNDS, TARGETS, AND COUNTER TARGETS | SRI INTERNATIONAL (US) | 2023-12-07 | — | — | US | disclosed |
| EP-4229211-A1 | BINDING ASSAYS INVOLVING A PLURALITY OF SYNTHETIC COMPOUNDS, TARGETS, AND COUNTER TARGETS | SRI International (US) | 2023-08-23 | — | — | EP | disclosed |
| WO-2022082006-A1 | BINDING ASSAYS INVOLVING A PLURALITY OF SYNTHETIC COMPOUNDS, TARGETS, AND COUNTER TARGETS | SRI INTERNATIONAL (US) | 2022-04-21 | — | — | WO | disclosed |