Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 3/20 | 0.53 |
| ▸ | CTSS | P25774 | 3/20 | 0.53 |
| ▸ | CTSK | P43235 | 3/20 | 0.53 |
| ▸ | CTSH | P09668 | 1/20 | 0.53 |
| ▸ | APLNR | P35414 | 2/20 | 0.52 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.49 |
| ▸ | RAMP3 | O60896 | 10/20 | 0.46 |
| ▸ | CALCR | P30988 | 10/20 | 0.46 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.45 |
| ▸ | MC4R | P32245 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29531535 | 0.88 | APLNR (0.54) | CTSLCTSSCTSKCTSHAPLNR | |
| SCHEMBL30398324 | 0.87 | APLNR (0.54) | CTSLCTSSCTSKCTSHAPLNR | |
| SCHEMBL30883198 | 0.86 | APLNR (0.57) | CTSLCTSSCTSKCTSHAPLNR | |
| SCHEMBL31157044 | 0.86 | CTSL (0.52) | CTSLCTSSCTSKCTSHAPLNR | |
| SCHEMBL29551839 | 0.85 | APLNR (0.55) | CTSLCTSSCTSKCTSHAPLNR | |
| SCHEMBL9295105 | 0.85 | C5AR1 (0.52) | CTSLCTSSCTSKCTSHAPLNR | |
| SCHEMBL30720014 | 0.85 | APLNR (0.54) | CTSLCTSSCTSKCTSHAPLNR | |
| SCHEMBL30753782 | 0.85 | APLNR (0.57) | APLNRC5AR1EPHA2 | |
| SCHEMBL30277111 | 0.84 | CTSL (0.56) | CTSLCTSSCTSKCTSHAPLNR | |
| SCHEMBL30458060 | 0.84 | APLNR (0.62) | CTSLCTSSCTSKCTSHAPLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117327148-B | Preparation and application of polypeptide targeting brain glioma and radionuclide labeled molecular probe | 中国科学院近代物理研究所 | 2024-11-15 | — | — | CN | claimed |
| CN-117327148-B | Preparation and application of polypeptide targeting brain glioma and radionuclide labeled molecular probe | 中国科学院近代物理研究所 | 2024-11-15 | — | — | CN | disclosed |
| CN-117442745-A | Liposome drug delivery system for targeted treatment of glioblastoma, and preparation method and application thereof | 中国科学院近代物理研究所 | 2024-01-26 | — | — | CN | disclosed |