SCHEMBL29531643

SCHEMBL29531643

C[C@@H](O)[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(=O)O)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](N)Cc1ccccc1)[C@@H](C)O)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ OPRD1 P41143 6/20 0.56
▸ OPRM1 P35372 2/20 0.56
▸ KISS1R Q969F8 3/20 0.53
▸ BACE1 P56817 1/20 0.52
▸ BACE2 Q9Y5Z0 1/20 0.52
▸ F2 P00734 2/20 0.51
▸ CCKAR P32238 3/20 0.51
▸ CCKBR P32239 3/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29531229 1.00 OPRD1 (0.56) OPRD1OPRM1KISS1RBACE1BACE2
SCHEMBL29530787 0.96 OPRD1 (0.50) OPRD1OPRM1KISS1RBACE1BACE2
SCHEMBL29531082 0.95 OPRM1 (0.56) OPRD1OPRM1KISS1RBACE1BACE2
SCHEMBL29531626 0.95 OPRM1 (0.56) OPRD1OPRM1KISS1RBACE1BACE2
SCHEMBL29531061 0.92 OPRD1 (0.57) OPRD1OPRM1KISS1RBACE1BACE2
SCHEMBL30522108 0.92 OPRM1 (0.56) OPRD1OPRM1KISS1R
SCHEMBL30733209 0.91 NPY1R (0.51) OPRD1KISS1RBACE1BACE2F2
SCHEMBL30401037 0.91 NPY1R (0.53) OPRD1KISS1RBACE1BACE2F2
SCHEMBL29530540 0.91 OPRM1 (0.49) OPRD1OPRM1KISS1RBACE1BACE2
SCHEMBL30337387 0.90 NPY4R (0.52) OPRD1OPRM1BACE1BACE2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12312390-B2 Rapid-acting insulin analogues of enhanced stability CASE WESTERN RESERVE UNIVERSITY (US) 2025-05-27 — — US disclosed
US-20230272004-A1 RAMP TAG FOR INSULIN OVEREXPRESSION AND METHOD FOR MANUFACTURING INSULIN USING SAME POLUS INC (KR) 2023-08-31 — — US disclosed
US-20220112262-A1 RAPID-ACTING INSULIN ANALOGUES OF ENHANCED STABILITY CASE WESTERN RESERVE UNIVERSITY 2022-04-14 — — US disclosed
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