Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 1/20 | 0.60 |
| ▸ | CDYL2 | Q8N8U2 | 8/20 | 0.50 |
| ▸ | CDYL | Q9Y232 | 8/20 | 0.50 |
| ▸ | CBX7 | O95931 | 7/20 | 0.50 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 6/20 | 0.50 |
| ▸ | CD74 | P04233 | 2/20 | 0.47 |
| ▸ | MIF | P14174 | 2/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.42 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | TSPO | P30536 | 1/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2955732 | 0.90 | KMO (0.51) | KMOCDYL2CDYLCBX7CDY1; CDY1B | |
| SCHEMBL2949061 | 0.85 | KMO (0.45) | KMOCDYL2CDYLCBX7CDY1; CDY1B | |
| SCHEMBL2950965 | 0.75 | KMO (0.76) | KMOCDYL2CDYLCBX7CDY1; CDY1B | |
| SCHEMBL29957877 | 0.75 | KMO (0.76) | KMOCDYL2CDYLCBX7CDY1; CDY1B | |
| SCHEMBL2800092 | 0.74 | AKR1C3 (0.42) | AKR1C3AKR1C2AKR1C1PTGS1KDM4E | |
| SCHEMBL14615630 | 0.74 | KMO (0.67) | KMOCDYL2CDYLCBX7CDY1; CDY1B | |
| SCHEMBL14615642 | 0.72 | KMO (0.52) | KMOALDH1A1SMN1; SMN2 | |
| SCHEMBL27033393 | 0.71 | CDYL2 (0.69) | KMOCDYL2CDYLCBX7CDY1; CDY1B | |
| SCHEMBL29958210 | 0.71 | CDYL2 (0.69) | KMOCDYL2CDYLCBX7CDY1; CDY1B | |
| SCHEMBL13099996 | 0.71 | CDYL2 (0.64) | KMOCDYL2CDYLCBX7CDY1; CDY1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7749998-B2 | Morpholinyl and pyrrolidinyl analogs | GLAXOSMITHKLINE LLC (US) | 2010-07-06 | — | — | US | disclosed |
| US-20090275571-A1 | MORPHOLINYL AND PYRROLIDINYL ANALOGS | SMITHKLINE BEECHAM CORPORATION | 2009-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090275571-A1 | MORPHOLINYL AND PYRROLIDINYL ANALOGS | UTS2R, AVPR2, VIPR2 | KMO 4460/4885CDYL2 3216/4885CDYL 4158/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.