Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP3 | Q9NY33 | 5/20 | 0.53 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.53 |
| ▸ | CTSB | P07858 | 2/20 | 0.53 |
| ▸ | GHSR | Q92847 | 2/20 | 0.52 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.51 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.51 |
| ▸ | ITGAL | P20701 | 1/20 | 0.51 |
| ▸ | NTSR2 | O95665 | 1/20 | 0.49 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.49 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.49 |
| ▸ | TACR1 | P25103 | 1/20 | 0.48 |
| ▸ | ACE | P12821 | 1/20 | 0.48 |
| ▸ | ECE1 | P42892 | 5/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29534382 | 1.00 | DPP3 (0.53) | DPP3CAPN1CTSBGHSRITGB2 | |
| SCHEMBL29534025 | 1.00 | DPP3 (0.53) | DPP3CAPN1CTSBGHSRITGB2 | |
| SCHEMBL30668967 | 0.98 | DPP3 (0.55) | DPP3CAPN1CTSBGHSRITGB2 | |
| SCHEMBL30051356 | 0.95 | ITGB2 (0.56) | DPP3GHSRITGB2ICAM1ITGAL | |
| SCHEMBL22459075 | 0.87 | GHSR (0.55) | DPP3CAPN1CTSBGHSRNTSR2 | |
| SCHEMBL6880238 | 0.86 | DPP3 (0.53) | DPP3GHSRITGB2ICAM1ITGAL | |
| SCHEMBL6877616 | 0.86 | DPP3 (0.53) | DPP3GHSRITGB2ICAM1ITGAL | |
| SCHEMBL29533411 | 0.86 | GHSR (0.65) | GHSRITGB2ICAM1ITGALACE | |
| SCHEMBL14903300 | 0.85 | DPP3 (0.53) | DPP3ITGB2ICAM1ITGALTACR1 | |
| SCHEMBL29812309 | 0.84 | DPP3 (0.64) | DPP3GHSRITGB2ICAM1ITGAL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114380889-A | Humanized ACE2 polypeptide retarder as well as design and synthesis method and application thereof | 中国科学院大连化学物理研究所 | 2022-04-22 | — | — | CN | claimed |
| CN-114380889-A | Humanized ACE2 polypeptide retarder as well as design and synthesis method and application thereof | 中国科学院大连化学物理研究所 | 2022-04-22 | — | — | CN | disclosed |