SCHEMBL30051356

SCHEMBL30051356

O=C(O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1

nearest known ligand 0.56

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ ITGB2 P05107 1/20 0.56
▸ ICAM1 P05362 1/20 0.56
▸ ITGAL P20701 1/20 0.56
▸ DPP3 Q9NY33 5/20 0.55
▸ TACR1 P25103 3/20 0.51
▸ GHSR Q92847 1/20 0.51
▸ ACE P12821 2/20 0.49
▸ MEN1 O00255 1/20 0.49
▸ KMT2A Q03164 1/20 0.49
▸ ALOX15 P16050 1/20 0.48
▸ BCHE P06276 1/20 0.48
▸ ECE1 P42892 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30668967 0.97 DPP3 (0.55) ITGB2ICAM1ITGALDPP3TACR1
SCHEMBL29534382 0.95 DPP3 (0.53) ITGB2ICAM1ITGALDPP3TACR1
SCHEMBL29534025 0.95 DPP3 (0.53) ITGB2ICAM1ITGALDPP3TACR1
SCHEMBL29533342 0.95 DPP3 (0.53) ITGB2ICAM1ITGALDPP3TACR1
SCHEMBL6880238 0.91 DPP3 (0.53) ITGB2ICAM1ITGALDPP3TACR1
SCHEMBL6877616 0.91 DPP3 (0.53) ITGB2ICAM1ITGALDPP3TACR1
SCHEMBL14903300 0.89 DPP3 (0.53) ITGB2ICAM1ITGALDPP3TACR1
SCHEMBL29812309 0.89 DPP3 (0.64) ITGB2ICAM1ITGALDPP3TACR1
SCHEMBL22459075 0.87 GHSR (0.55) DPP3TACR1GHSRMEN1KMT2A
SCHEMBL30921658 0.86 ITGB2 (0.65) ITGB2ICAM1ITGALDPP3TACR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113754719-B Tripeptide and application thereof in preparation of medicines and health products for improving memory 荣成泰祥食品股份有限公司 2023-08-04 — — CN claimed
US-12622975-B2 Peptide-conjugated prodrugs BRANDEIS UNIVERSITY (US) 2026-05-12 — — US disclosed
CN-113754719-B Tripeptide and application thereof in preparation of medicines and health products for improving memory 荣成泰祥食品股份有限公司 2023-08-04 — — CN disclosed
CN-113754719-B Tripeptide and application thereof in preparation of medicines and health products for improving memory 荣成泰祥食品股份有限公司 2023-08-04 — — CN disclosed
US-20220387610-A1 PEPTIDE-CONJUGATED PRODRUGS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2022-12-08 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12622975-B2 Peptide-conjugated prodrugs PEPD, PAM, VIP ITGB2 3494/4885ICAM1 2949/4885ITGAL 2468/4885
US-20220387610-A1 PEPTIDE-CONJUGATED PRODRUGS VIP, DNPEP, PEPD ITGB2 3719/4885ICAM1 2371/4885ITGAL 2907/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback