SCHEMBL2953434

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2954483	0.95	LMNA (0.49)	MEN1KMT2ALMNAPOLBCYP1A2
	SCHEMBL2948823	0.91	CYP1A2 (0.47)	MEN1KMT2ALMNAPOLBCYP1A2
	SCHEMBL2944730	0.89	KMT2A (0.43)	MEN1KMT2ALMNAPOLBADORA3
	SCHEMBL2950038	0.89	KMT2A (0.46)	MEN1KMT2ALMNAPOLBPTPN1
	SCHEMBL2950504	0.88	MEN1 (0.50)	MEN1KMT2ALMNAPOLBADORA3
	SCHEMBL2953069	0.88	PDE4B (0.44)	MEN1KMT2ALMNAPOLBCYP1A2
	SCHEMBL2952835	0.88	MEN1 (0.44)	MEN1KMT2ALMNAPOLBPTPN1
	SCHEMBL2945524	0.86	KMT2A (0.43)	MEN1KMT2ALMNAPOLBCYP1A2
	SCHEMBL2953911	0.86	GAA (0.48)	MEN1KMT2ALMNAPOLBCYP1A2
	SCHEMBL13236915	0.85	TP53 (0.47)	MEN1KMT2ALMNAPOLBADORA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.