SCHEMBL29535577

SCHEMBL29535577

COc1nc(-c2ccccc2)nnc1-c1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 1.00
NPC1 O15118 2/20 1.00
RAB9A P51151 2/20 1.00
NFKB1 P19838 1/20 1.00
NFKB2 Q00653 1/20 1.00
RELA Q04206 1/20 1.00
ALDH1A1 P00352 1/20 0.54
KMT2A Q03164 3/20 0.53
MAPT P10636 3/20 0.50
MEN1 O00255 2/20 0.50
LMNA P02545 1/20 0.50
MAPK1 P28482 1/20 0.46
ADORA2A P29274 1/20 0.46
ADORA1 P30542 1/20 0.46
SQOR Q9Y6N5 1/20 0.44
KDM4E B2RXH2 1/20 0.44
PKM P14618 1/20 0.44
GAA P10253 1/20 0.44
WHR1 P49842 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3445210 0.76 SMN1; SMN2 (0.81) SMN1; SMN2NPC1RAB9ANFKB1NFKB2
SCHEMBL14985964 0.75 NPC1 (0.59) SMN1; SMN2NPC1RAB9ANFKB1NFKB2
SCHEMBL14280963 0.75 SMN1; SMN2 (0.59) SMN1; SMN2NPC1RAB9ANFKB1NFKB2
SCHEMBL2849974 0.74 ALDH1A1 (0.81) SMN1; SMN2NPC1RAB9ANFKB1NFKB2
SCHEMBL32668864 0.74 ALDH1A1 (0.81) SMN1; SMN2NPC1RAB9ANFKB1NFKB2
SCHEMBL29556760 0.74 ALDH1A1 (0.81) SMN1; SMN2NPC1RAB9ANFKB1NFKB2
SCHEMBL7735370 0.73 KDM4E (0.65) SMN1; SMN2NPC1RAB9ANFKB1NFKB2
SCHEMBL16232472 0.73 SMN1; SMN2 (0.58) SMN1; SMN2NPC1RAB9ANFKB1NFKB2
SCHEMBL13108734 0.72 ALDH1A1 (0.79) SMN1; SMN2NPC1RAB9ANFKB1NFKB2
SCHEMBL27956430 0.72 ALDH1A1 (0.69) SMN1; SMN2NPC1RAB9ANFKB1NFKB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026087411-A1 NUCLEIC ACID REGULATORY ELEMENTS AND METHODS OF USING MeiraGTx Gene Regulation Limited (GB) 2026-04-30 WO disclosed
EP-4590291-A1 SAGERINIC ACID AND COMPOSITIONS CONTAINING SAME, FOR USE IN THE PREVENTION AND/OR TREATMENT OF SENESCENCE-RELATED DISORDERS IN A HUMAN OR ANIMAL A2P Sciences (FR) 2025-07-30 EP disclosed
CN-119907665-A Salicylic acid and compositions comprising the same for use in the prevention and/or treatment of aging-related disorders in humans or animals A2P科学公司 2025-04-29 CN disclosed
CN-116298000-B Detection method of Xuanqitong bi capsules fingerprint 南京中山制药有限公司 2025-04-29 CN disclosed
CN-116087392-B Detection method for detecting finger print and content measurement of hovenia dulcis thunb particles 江苏弘典中药产业研究院有限公司 2025-03-28 CN disclosed
CN-115112802-B Qualitative or quantitative analysis method for monosaccharide-glycosidic bond connection mode of traditional Chinese medicine polysaccharide 梁军 2025-02-11 CN disclosed
CN-119120217-A Application of penicillium oxalicum in degradation of metolachlor and promotion of soil phosphate dissolution and preparation containing penicillium oxalicum 农业农村部环境保护科研监测所 2024-12-13 CN disclosed
CN-114858960-B Glycosidic bond connection mode analysis database and construction method and application thereof 梁军 2024-09-10 CN disclosed
CN-118415223-A Compound antifreeze agent capable of improving freezing storage quality of pregelatinized product and application thereof 宁波大学 2024-08-02 CN disclosed
CN-114295738-B Quality detection method of red sage leaf tea 江苏弘典中药产业研究院有限公司 2024-04-02 CN disclosed
CN-114858960-A Glycosidic bond connection mode analysis database and construction method and application thereof 梁军 2022-08-05 CN disclosed
CN-114839292-A Biomarker for excessive heat and excessive fire syndrome intervened by coptis antidote pill and application of biomarker 中国中医科学院中药研究所 2022-08-02 CN disclosed
CN-111487351-B Method for detecting fingerprint of blood-activating pain-relieving capsule 江苏弘典中药产业研究院有限公司 2022-07-26 CN disclosed
CN-111487347-B Method for detecting fingerprint of Zhishu granules 江苏弘典中药产业研究院有限公司 2022-07-15 CN disclosed
CN-111948330-B Detection method of finger-print of Renzhu stomach-invigorating granules 江苏弘典中药产业研究院有限公司 2022-06-17 CN disclosed
CN-111487344-B Method for detecting fingerprint spectrum of motherwort particles 江苏弘典中药产业研究院有限公司 2022-06-10 CN disclosed
CN-111487335-B Method for detecting fingerprint of Xiao' er Ganmaoshu granules 江苏弘典中药产业研究院有限公司 2022-05-17 CN disclosed
CN-114295738-A Quality detection method of salvia miltiorrhiza leaf tea 江苏弘典中药产业研究院有限公司 2022-04-08 CN disclosed
CN-114252521-A Detection method of fingerprint of Chinese medicine Chinese lobelia 江苏弘典中药产业研究院有限公司 2022-03-29 CN disclosed
CN-114137131-A Construction and application of partially methylated glycolonitrile acetate retention index database 夏永刚 2022-03-04 CN disclosed