SCHEMBL29535616

SCHEMBL29535616

Brc1cccc2c1ncn2Br

nearest known ligand 0.41

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GRM2 Q14416 15/20 0.41
PRPS1 P60891 1/20 0.36
BACE1 P56817 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9981117 0.78 GRM2 (0.45) GRM2PRPS1
SCHEMBL20471908 0.78 TLR8 (0.37)
SCHEMBL15392834 0.73 GRM2 (0.40) GRM2PRPS1
SCHEMBL7605205 0.73 EGLN1 (0.46) GRM2
SCHEMBL12970517 0.73 GRM2 (0.51) GRM2PRPS1
SCHEMBL900261 0.71 GRM2 (0.46) GRM2
SCHEMBL901131 0.70 CYP17A1 (0.56) GRM2
SCHEMBL23852698 0.70 PRPS1 (0.42) GRM2PRPS1
SCHEMBL4855166 0.70 CYP11B1 (0.58) GRM2
SCHEMBL17009438 0.70 GRM2 (0.38) GRM2PRPS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110152739-B Porous organic compound of in-situ supported palladium nanoparticles, synthetic method and application 山东师范大学 2022-04-15 CN disclosed