Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A2 | P31639 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.40 |
| ▸ | MPO | P05164 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.34 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.34 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.34 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.32 |
| ▸ | TUBB | P07437 | 1/20 | 0.32 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.32 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.32 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.32 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.32 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.32 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12181546 | 0.71 | MPO (0.42) | MPOCYP11B2 | |
| SCHEMBL1842778 | 0.70 | CYP11B2 (0.44) | MPOCYP11B2 | |
| SCHEMBL4924021 | 0.70 | MPO (0.44) | MPOCYP11B2 | |
| SCHEMBL5263383 | 0.70 | MPO (0.41) | MPOCYP11B2 | |
| SCHEMBL29536485 | 0.70 | SLC6A4 (0.41) | SLC5A2SLC6A4SLC6A2SLC6A3TBXA2R | |
| SCHEMBL29798879 | 0.68 | SLC6A4 (0.42) | SLC6A4SLC6A2SLC6A3TBXA2RPTGER3 | |
| SCHEMBL21092871 | 0.68 | CYP11B2 (0.41) | MPOCYP11B2 | |
| SCHEMBL9471608 | 0.66 | SLC5A2 (0.44) | SLC5A2SLC6A4SLC5A1 | |
| SCHEMBL13026656 | 0.66 | SLC6A4 (0.56) | SLC6A4SLC6A2SLC6A3MAOA | |
| SCHEMBL2046936 | 0.63 | TSHR (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3976053-A1 | COMPOSITIONS AND METHODS FOR TREATING METABOLIC DISEASE | Avolynt (US) | 2022-04-06 | — | — | EP | disclosed |