Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 2/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
| ▸ | AXL | P30530 | 1/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4924021 | 0.82 | MPO (0.44) | MPOCYP11B2KDM4ECYP1A2CYP2C9 | |
| SCHEMBL5263383 | 0.82 | MPO (0.41) | MPOCYP11B2KDM4ECYP1A2CYP2C9 | |
| SCHEMBL1842778 | 0.82 | CYP11B2 (0.44) | MPOCYP11B2KDM4ECYP1A2CYP2C9 | |
| SCHEMBL16229203 | 0.82 | ALDH1A1 (0.30) | CYP11B2ALDH1A1 | |
| SCHEMBL17653890 | 0.80 | AGBL2 (0.40) | MPOCYP11B2KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL14707646 | 0.78 | MPO (0.46) | MPOCYP11B2CYP1A2SMN1; SMN2GAA | |
| SCHEMBL17653924 | 0.77 | CCNE1 (0.38) | MPOCYP11B2KDM4EALDH1A1MEN1 | |
| SCHEMBL27324058 | 0.76 | LMNA (0.41) | MPOCYP11B2KDM4ECYP1A2ALDH1A1 | |
| SCHEMBL25145864 | 0.74 | CACNA1H (0.39) | MPOCYP11B2CDK2 | |
| SCHEMBL1196081 | 0.73 | POLB (0.57) | CYP11B2KDM4ESMN1; SMN2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230242531-A1 | Monoacylglycerol Lipase Modulators | JANSSEN PHARMACEUTICA NV (BE) | 2023-08-03 | — | — | US | disclosed |
| US-10023532-B2 | Alkyl phenyl sulfide derivative and pest control agent | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2018-07-17 | — | — | US | disclosed |
| US-10023532-B2 | Alkyl phenyl sulfide derivative and pest control agent | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2018-07-17 | — | — | US | disclosed |
| US-20160214932-A1 | ALKYL PHENYL SULFIDE DERIVATIVE AND PEST CONTROL AGENT | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2016-07-28 | — | — | US | disclosed |
| US-20160214932-A1 | ALKYL PHENYL SULFIDE DERIVATIVE AND PEST CONTROL AGENT | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2016-07-28 | — | — | US | disclosed |
| US-9332754-B2 | Alkyl phenyl sulfide derivative and pest control agent | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2016-05-10 | — | — | US | disclosed |
| US-20150087833-A1 | ALKYL PHENYL SULFIDE DERIVATIVE AND PEST CONTROL AGENT | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2015-03-26 | — | — | US | disclosed |
| US-20130012511-A1 | SOLUBLE GUANYLATE CYCLASE ACTIVATORS | MERCK SHARP & DOHME LLC | 2013-01-10 | — | — | US | disclosed |
| WO-2011145035-A1 | NOVEL 3,5-DISUBSTITUED-3H-IMIDAZO[4,5-B]PYRIDINE AND 3,5- DISUBSTITUED -3H-[1,2,3]TRIAZOLO[4,5-B] PYRIDINE COMPOUNDS AS MODULATORS OF PROTEIN KINASES | INDIAN INCOZEN THERAPEUTICS PVT. LTD. (IN) | 2011-11-24 | — | — | WO | disclosed |
| US-20080312435-A1 | Imine Compound | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2008-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080312435-A1 | Imine Compound | CNR1, CNR2, HRH4 | MPO 1767/4885CYP11B2 1428/4885KDM4E 3386/4885 |
| US-20230242531-A1 | Monoacylglycerol Lipase Modulators | MGLL, LPL, PNLIP | MPO 321/4885CYP11B2 1907/4885KDM4E 2800/4885 |
| US-20150087833-A1 | ALKYL PHENYL SULFIDE DERIVATIVE AND PEST CONTROL AGENT | C1S, TRPA1, STK39 | MPO 4500/4885CYP11B2 2673/4885KDM4E 1417/4885 |
| US-20130012511-A1 | SOLUBLE GUANYLATE CYCLASE ACTIVATORS | PDE3B, PDE3A, GUCY1B1 | MPO 1269/4885CYP11B2 177/4885KDM4E 2697/4885 |
| US-20160214932-A1 | ALKYL PHENYL SULFIDE DERIVATIVE AND PEST CONTROL AGENT | C1S, TRPA1, STK39 | MPO 4500/4885CYP11B2 2673/4885KDM4E 1417/4885 |
| US-10023532-B2 | Alkyl phenyl sulfide derivative and pest control agent | C1S, TRPA1, STK39 | MPO 4500/4885CYP11B2 2673/4885KDM4E 1417/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.