Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 4/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.40 |
| ▸ | MET | P08581 | 9/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 2/20 | 0.35 |
| ▸ | BRAF | P15056 | 1/20 | 0.35 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25420084 | 1.00 | PDE4B (0.40) | PDE4BPDE4APDE4CPDE4DPDE3B | |
| SCHEMBL26075423 | 0.86 | RAF1 (0.48) | KDRBRAF | |
| SCHEMBL29537104 | 0.85 | MET (0.35) | PDE4BMETBRD4 | |
| SCHEMBL25420591 | 0.85 | MET (0.35) | PDE4BMETBRD4 | |
| SCHEMBL29537702 | 0.84 | PTGS2 (0.33) | MET | |
| SCHEMBL26075465 | 0.84 | PTGS2 (0.33) | MET | |
| SCHEMBL25421713 | 0.81 | MET (0.37) | METKDRBRAF | |
| SCHEMBL29537267 | 0.80 | MET (0.37) | METKDR | |
| SCHEMBL29537371 | 0.77 | MET (0.32) | PDE4BMETKDR | |
| SCHEMBL29536773 | 0.77 | EPHX2 (0.44) | METALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116710453-A | Kinase inhibitors and uses thereof | 璧辰医药技术股份有限公司 | 2023-09-05 | — | — | CN | disclosed |
| EP-4192582-A1 | KINASE INHIBITORS AND USES THEREOF | ABM Therapeutics Corporation (US) | 2023-06-14 | — | — | EP | disclosed |
| WO-2022032071-A1 | KINASE INHIBITORS AND USES THEREOF | ABM THERAPEUTICS CORPORATION (US) | 2022-02-10 | — | — | WO | disclosed |