Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 18/20 | 0.34 |
| ▸ | KDR | P35968 | 9/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | KIT | P10721 | 1/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | AXL | P30530 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26075468 | 0.85 | MET (0.48) | METKDRRETKITPDGFRA | |
| SCHEMBL26075420 | 0.74 | RAF1 (0.47) | KDRRET | |
| SCHEMBL26074956 | 0.73 | MET (0.51) | METKDRRETKITPDGFRA | |
| SCHEMBL29537267 | 0.70 | MET (0.37) | METKDRRETKITPDGFRA | |
| SCHEMBL29537071 | 0.69 | MAPK14 (0.34) | METKDRRETKITPDGFRA | |
| SCHEMBL25421713 | 0.67 | MET (0.37) | METKDR | |
| SCHEMBL29537371 | 0.67 | MET (0.32) | METKDRRETKITPDGFRA | |
| SCHEMBL30590717 | 0.67 | EGFR (0.45) | — | |
| SCHEMBL26076556 | 0.67 | EGFR (0.45) | — | |
| SCHEMBL29536806 | 0.67 | PDE4B (0.40) | METKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4192582-A1 | KINASE INHIBITORS AND USES THEREOF | ABM Therapeutics Corporation (US) | 2023-06-14 | — | — | EP | disclosed |
| WO-2022032071-A1 | KINASE INHIBITORS AND USES THEREOF | ABM THERAPEUTICS CORPORATION (US) | 2022-02-10 | — | — | WO | disclosed |