Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 6/20 | 0.37 |
| ▸ | CDK2 | P24941 | 10/20 | 0.36 |
| ▸ | CDK4 | P11802 | 5/20 | 0.36 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.34 |
| ▸ | IKBKB | O14920 | 1/20 | 0.33 |
| ▸ | CHUK | O15111 | 1/20 | 0.33 |
| ▸ | PRKCA | P17252 | 1/20 | 0.33 |
| ▸ | PRKCI | P41743 | 1/20 | 0.33 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24286074 | 1.00 | TGFBR1 (0.37) | TGFBR1CDK2CDK4RPS6KA3IKBKB | |
| SCHEMBL24285926 | 0.90 | CDK2 (0.37) | TGFBR1CDK2CDK4RPS6KA3 | |
| SCHEMBL29537942 | 0.90 | CDK2 (0.37) | TGFBR1CDK2CDK4RPS6KA3 | |
| SCHEMBL29537492 | 0.86 | CDK2 (0.35) | TGFBR1CDK2CDK4RPS6KA3IKBKB | |
| SCHEMBL24286063 | 0.86 | CDK2 (0.35) | TGFBR1CDK2CDK4RPS6KA3IKBKB | |
| SCHEMBL24285965 | 0.82 | PRKCA (0.35) | TGFBR1RPS6KA3PRKCAPRKCIPRKCE | |
| SCHEMBL29537655 | 0.82 | PRKCA (0.35) | TGFBR1RPS6KA3PRKCAPRKCIPRKCE | |
| SCHEMBL24286202 | 0.81 | ABL1 (0.44) | — | |
| SCHEMBL24285984 | 0.81 | RIPK1 (0.47) | CDK2 | |
| SCHEMBL29537181 | 0.81 | RIPK1 (0.47) | CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4214207-A1 | 2-AMINO-3-CARBONYL IMIDAZOPYRIDINE AND PYRAZOLOPYRIDINE COMPOUNDS | 1st Biotherapeutics, Inc. (KR) | 2023-07-26 | — | — | EP | claimed |
| CN-116457355-A | 2-amino-3-carbonyl imidazopyridines and pyrazolopyridines compounds | 第一生物治疗股份有限公司 | 2023-07-18 | — | — | CN | claimed |
| WO-2022058890-A1 | 2-AMINO-3-CARBONYL IMIDAZOPYRIDINE AND PYRAZOLOPYRIDINE COMPOUNDS | 1ST Biotherapeutics, Inc. (KR) | 2022-03-24 | — | — | WO | claimed |