SCHEMBL2954

SCHEMBL2954

O=c1c2ccccc2nnn1O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.57
KMT2A Q03164 2/20 0.57
SMN1; SMN2 Q16637 6/20 0.56
ALDH1A1 P00352 2/20 0.56
CYP1A2 P05177 1/20 0.56
CYP2C19 P33261 1/20 0.56
POLB P06746 1/20 0.53
MAPK1 P28482 1/20 0.53
ATM Q13315 1/20 0.53
NPC1 O15118 4/20 0.53
RAB9A P51151 4/20 0.53
GAA P10253 1/20 0.49
KDM4E B2RXH2 1/20 0.49
LMNA P02545 3/20 0.47
MAPT P10636 1/20 0.47
HTT P42858 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
PTBP1 P26599 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
TSHR P16473 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29350840 1.00 MEN1 (0.57) MEN1KMT2ASMN1; SMN2ALDH1A1CYP1A2
SCHEMBL4884291 0.98 MEN1 (0.56) MEN1KMT2ASMN1; SMN2ALDH1A1CYP1A2
SCHEMBL9988541 0.86 MEN1 (0.46) MEN1KMT2ASMN1; SMN2ALDH1A1CYP1A2
SCHEMBL7619385 0.79 KDM4E (0.49) MEN1KMT2ASMN1; SMN2ALDH1A1CYP1A2
SCHEMBL537962 0.78 SMN1; SMN2 (0.58) MEN1KMT2ASMN1; SMN2ALDH1A1CYP1A2
SCHEMBL7607425 0.76 SMN1; SMN2 (0.56) MEN1KMT2ASMN1; SMN2ALDH1A1CYP1A2
SCHEMBL904817 0.76 ALDH1A1 (0.62) MEN1KMT2ASMN1; SMN2ALDH1A1CYP1A2
SCHEMBL14438168 0.76 SMN1; SMN2 (0.56) MEN1KMT2ASMN1; SMN2ALDH1A1CYP1A2
SCHEMBL7606134 0.76 ALDH1A1 (0.56) MEN1KMT2ASMN1; SMN2ALDH1A1CYP1A2
SCHEMBL11349671 0.76 MEN1 (0.76) MEN1KMT2ASMN1; SMN2ALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5465 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4741451-A1 METHOD FOR DEGRADING A VINYL POLYMER Centre National de la Recherche Scientifique (FR) 2026-05-13 EP claimed
WO-2026090160-A2 CD4-TARGETED IL-15 MOLECULES AND METHODS OF USE GILEAD SCIENCES, INC. (US) 2026-04-30 WO claimed
EP-4662222-A1 PROCESS FOR THE PREPARATION OF TETRAPEPTIDE FRAGMENT OF LIRAGLUTIDE Fresenius Kabi Oncology Ltd (IN) 2025-12-17 EP claimed
US-20250340518-A1 PROCESS FOR PREPARATION OF SELUMETINIB AND SALTS THEREOF GLENMARK LIFE SCIENCES LTD (IN) 2025-11-06 US claimed
US-12454526-B2 Method for producing pyrrole-imidazole (poly)amide KANEKA CORPORATION (JP) 2025-10-28 US claimed
EP-4615902-A1 IDEAL STRUCTURE AND SCALABLE FABRICATION METHODS The Regents of the University of California (US) 2025-09-17 EP claimed
US-20250276995-A1 PRODUCTION METHOD FOR PEPTIDE COMPOUND CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-09-04 US claimed
WO-2025149985-A1 METHODS OF PREPARING MELANOCORTIN 4 RECEPTOR AGONISTS LG CHEM, LTD. (KR) 2025-07-17 WO claimed
CN-120192237-A Synthesis and application of novel non-classical solid phase synthesis carrier 瑞博(苏州)制药有限公司 2025-06-24 CN claimed
CN-120040555-A CXCR4 targeted dimer molecular probe and preparation method and application thereof 哈尔滨医科大学 2025-05-27 CN claimed
EP-0027258-B1 PHOSPHORYL MURAMYL PEPTIDES, METHOD FOR THEIR PREPARATION AND THEIR USE IN MEDICINES CIBA-GEIGY AG (CH) 1985-05-15 EP claimed
EP-0025495-B1 LIPOPHILIC MURAMYL PEPTIDES, PROCESSES FOR THEIR PREPARATION AND THEIR USE CIBA-GEIGY AG (CH) 1984-06-20 EP claimed
EP-0014911-B1 DIPEPTIDE (PYRO)GLU-HIS(DNP)-OH AND PROCESS FOR THE PREPARATION OF LH-RH AND OF ANALOGS OF LH-RH USING THE SAID DIPEPTIDE HOECHST AKTIENGESELLSCHAFT (DE) 1983-01-26 EP claimed
EP-0056992-A1 Phosphorylated derivatives, pharmaceutical compositions containing such derivatives, and their use CIBA-GEIGY AG (CH) 1982-08-04 EP claimed
US-4275001-A Process for the manufacture of LH-RH and LH-RH analogs using Glu-His(DnP)-OH HOECHST AKTIENGESELLSCHAFT (DE) 1981-06-23 US claimed
EP-0027258-A1 Phosphoryl muramyl peptides, method for their preparation and their use in medicines CIBA-GEIGY AG (CH) 1981-04-22 EP claimed
EP-0025495-A1 Lipophilic muramyl peptides, processes for their preparation and their use CIBA-GEIGY AG (CH) 1981-03-25 EP claimed
US-4242507-A Sulfonic acid esters FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1980-12-30 US claimed
EP-0014911-A2 Dipeptide (pyro)Glu-His(Dnp)-OH and process for the preparation of LH-RH and of analogs of LH-RH using the said dipeptide HOECHST AKTIENGESELLSCHAFT (DE) 1980-09-03 EP claimed
US-4098779-A Process for the purification and manufacture of secretin HOECHST AKTIENGESELLSCHAFT (DE) 1978-07-04 US claimed