Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.53 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethane SCHEMBL11551567 | 0.88 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2CYP1A2CYP2C19MEN1 | |
| Methane SCHEMBL1965180 | 0.88 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2CYP1A2CYP2C19MEN1 | |
| SCHEMBL537962 | 0.78 | SMN1; SMN2 (0.58) | ALDH1A1SMN1; SMN2CYP1A2CYP2C19MEN1 | |
| SCHEMBL10328256 | 0.77 | FEN1 (0.42) | ALDH1A1KDM4EMAPTLMNAHTT | |
| SCHEMBL12247551 | 0.77 | ALDH1A1 (0.78) | ALDH1A1SMN1; SMN2CYP1A2CYP2C19MEN1 | |
| SCHEMBL29350840 | 0.76 | MEN1 (0.57) | ALDH1A1SMN1; SMN2CYP1A2CYP2C19MEN1 | |
| SCHEMBL7607425 | 0.76 | SMN1; SMN2 (0.56) | ALDH1A1SMN1; SMN2CYP1A2CYP2C19MEN1 | |
| SCHEMBL14438168 | 0.76 | SMN1; SMN2 (0.56) | ALDH1A1SMN1; SMN2CYP1A2CYP2C19MEN1 | |
| SCHEMBL2954 | 0.76 | MEN1 (0.57) | ALDH1A1SMN1; SMN2CYP1A2CYP2C19MEN1 | |
| SCHEMBL7606134 | 0.76 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2CYP1A2CYP2C19MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012166891-A2 | MU-OPIOID RECEPTOR BINDING COMPOUNDS | ALGYNOMICS INC. (US) | 2012-12-06 | — | — | WO | claimed |
| EP-4289813-A2 | INTERMEDIATES TO OBTAIN SUBSTITUTED BENZALDEHYDE COMPOUNDS AND METHODS FOR THEIR USE IN INCREASING TISSUE OXYGENATION | Global Blood Therapeutics, Inc. (US) | 2023-12-13 | — | — | EP | disclosed |
| CN-114835599-A | Preparation method of o-aryl benzamide compound | 绍兴久孚新材料科技有限公司 | 2022-08-02 | — | — | CN | disclosed |
| US-20220135614-A1 | SYNTHESIS OF BICYCLE TOXIN CONJUGATES, AND INTERMEDIATES THEREOF | Bicyclerd Limited (GB) | 2022-05-05 | — | — | US | disclosed |
| US-10851082-B2 | Substituted aromatic n-heterocyclic compounds as inhibitors of mitogen-activated protein kinase interacting kinase 1 (MNK1) and 2 (MNK2) | NORTHWESTERN UNIVERSITY (US) | 2020-12-01 | — | — | US | disclosed |
| EP-3738434-A1 | INTERMEDIATES TO OBTAIN SUBSTITUTED BENZALDEHYDE COMPOUNDS AND METHODS FOR THEIR USE IN INCREASING TISSUE OXYGENATION | Global Blood Therapeutics, Inc. (US) | 2020-11-18 | — | — | EP | disclosed |
| US-10791739-B2 | Binary compositions as disruptors of orco-mediated odorant sensing | VANDERBILT UNIVERSITY (US) | 2020-10-06 | — | — | US | disclosed |
| US-10781184-B2 | Substituted benzazinones as antibacterial compounds | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2020-09-22 | — | — | US | disclosed |
| US-20180092359-A1 | BINARY COMPOSITIONS AS DISRUPTORS OF ORCO-MEDIATED ODORANT SENSING | VANDERBILT UNIVERSITY | 2018-04-05 | — | — | US | disclosed |
| US-9730928-B2 | Trizol-1-OL analogs anti-retroviral latency drugs | UNIVERISTY OF UTAH RESEARCH FOUNDATION (US) | 2017-08-15 | — | — | US | disclosed |
| US-20080114169-A1 | Isotopically enriched N-substituted piperazines and methods for the preparation thereof | APPLIED BIOSYSTEMS, LLC | 2008-05-15 | — | — | US | disclosed |
| US-7355045-B2 | Isotopically enriched N-substituted piperazine acetic acids and methods for the preparation thereof | APPLERA CORPORATION (US) | 2008-04-08 | — | — | US | disclosed |
| US-20080020985-A1 | PHARMACEUTICAL COMPOUNDS AS ACTIVATORS OF CASPASES AND INDUCERS OF APOPTOSIS AND THE USE THEREOF | MYRIAD GENETICS, INC. (US) | 2008-01-24 | — | — | US | disclosed |
| US-7307169-B2 | Isotopically enriched N-substituted piperazines and methods for the preparation thereof | APPLERA CORPORATION (US) | 2007-12-11 | — | — | US | disclosed |
| US-20070269664-A1 | Gas Barrier Laminated Film and Process for Producing the Same | SAI NIPPON PRINTING CO., LTD. (JP) | 2007-11-22 | — | — | US | disclosed |
| US-20070269664-A1 | Gas Barrier Laminated Film and Process for Producing the Same | SAI NIPPON PRINTING CO., LTD. (JP) | 2007-11-22 | — | — | US | disclosed |
| EP-1833803-A2 | PHARMACEUTICAL COMPOUNDS AS ACTIVATORS OF CASPASES AND INDUCERS OF APOPTOSIS AND THE USE THEREOF | MYRIAD GENETICS, INC. (US) | 2007-09-19 | — | — | EP | disclosed |
| US-20070027296-A1 | Method for preparing poly (lactic acid)- based resin and its co-polymers | SHANGHAI TONG-JIE-LIANG BIOMATERIALS CO., LTD. (CN) | 2007-02-01 | — | — | US | disclosed |
| US-7157581-B2 | Monocyclic compounds and their use in medicine: process for their preparation and pharmaceutical compositions containing them | DR. REDDY'S LABORATORIES LTD. (IN) | 2007-01-02 | — | — | US | disclosed |
| WO-2006074223-A2 | PHARMACEUTICAL COMPOUNDS AS ACTIVATORS OF CASPASES AND INDUCERS OF APOPTOSIS AND THE USE THEREOF | MYRIAD GENETICS, INC. (US) | 2006-07-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10851082-B2 | Substituted aromatic n-heterocyclic compounds as inhibitors of mitogen-activated protein kinase interacting kinase 1 (MNK1) and 2 (MNK2) | MAP4K2, MAP3K20, MKNK2 | ALDH1A1 4646/4885SMN1; SMN2 452/4885CYP1A2 4568/4885 |
| US-20070269664-A1 | Gas Barrier Laminated Film and Process for Producing the Same | CDH1, VIL1, TET1 | ALDH1A1 2903/4885SMN1; SMN2 3275/4885CYP1A2 2849/4885 |
| US-20080114169-A1 | Isotopically enriched N-substituted piperazines and methods for the preparation thereof | ALKBH5, NPEPPS, PNMT | ALDH1A1 580/4885SMN1; SMN2 437/4885CYP1A2 833/4885 |
| US-20180092359-A1 | BINARY COMPOSITIONS AS DISRUPTORS OF ORCO-MEDIATED ODORANT SENSING | OR51E2, OR10J3, ORC3 | ALDH1A1 2668/4885SMN1; SMN2 3929/4885CYP1A2 2568/4885 |
| US-10781184-B2 | Substituted benzazinones as antibacterial compounds | LPXN, MLX, ZYX | ALDH1A1 2221/4885SMN1; SMN2 4553/4885CYP1A2 1428/4885 |
| US-20220135614-A1 | SYNTHESIS OF BICYCLE TOXIN CONJUGATES, AND INTERMEDIATES THEREOF | BTD, ANTXR2, CYCS | ALDH1A1 3317/4885SMN1; SMN2 3198/4885CYP1A2 660/4885 |
| US-20080020985-A1 | PHARMACEUTICAL COMPOUNDS AS ACTIVATORS OF CASPASES AND INDUCERS OF APOPTOSIS AND THE USE THEREOF | CASP3, CASP2, CASP5 | ALDH1A1 1221/4885SMN1; SMN2 2939/4885CYP1A2 859/4885 |
| US-10791739-B2 | Binary compositions as disruptors of orco-mediated odorant sensing | OR51E2, OR10J3, ORC3 | ALDH1A1 2668/4885SMN1; SMN2 3929/4885CYP1A2 2568/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.